Cardiac-specific overexpression of thioredoxin 1 attenuates mitochondrial and myocardial dysfunction in septic mice

Abstract: Sepsis-induced myocardial dysfunction is associated with increased oxidative stress and mitochondrial dysfunction. Current evidence suggests a protective role of thioredoxin-1 (Trx1) in the pathogenesis of cardiovascular diseases. However, it is unknown yet a putative role of Trx1 in sepsi...

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Autor Principal: Sánchez Villamil, Juana Patricia; D’Annunzio, Verónica; Finocchiettoa, Paola; Holodd, Silvia; Rebagliati, Inés; Pérez, Hernán; Peralta, Jorge G.; Gelpi, Ricardo J.; Poderoso, Juan J.; Carreras, María C.
Formato: Artículo (Article)
Lenguaje:Desconocido (Unknown)
Publicado: The International Journal of Biochemistry & Cell Biology; Vol. 81, Parte B 2016
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