Effects of supervised multimodal exercise interventions on cancer-related fatigue: systematic review and meta-analysis of randomized controlled trials

Objective. Cancer-related fatigue (CRF) is the most common and devastating problem in cancer patients even after successful treatment. This study aimed to determine the effects of supervised multimodal exercise interventions on cancer-related fatigue through a systematic review and meta-analysis....

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Autores Principales: Meneses-Echávez, José Francisco, González-Jiménez, Emilio, Ramírez-Vélez, Robinson
Formato: Desconocido (Unknown)
Publicado: 2019
Materias:
Acceso en línea:http://hdl.handle.net/11634/20382
id ir-11634-20382
recordtype dspace
institution Universidad Santo Tomas
collection DSpace
topic Multimodal Exercise Interventions
Meta-Analysis
Cancer-Related Fatigue
Effects
spellingShingle Multimodal Exercise Interventions
Meta-Analysis
Cancer-Related Fatigue
Effects
Meneses-Echávez, José Francisco
González-Jiménez, Emilio
Ramírez-Vélez, Robinson
Effects of supervised multimodal exercise interventions on cancer-related fatigue: systematic review and meta-analysis of randomized controlled trials
description Objective. Cancer-related fatigue (CRF) is the most common and devastating problem in cancer patients even after successful treatment. This study aimed to determine the effects of supervised multimodal exercise interventions on cancer-related fatigue through a systematic review and meta-analysis. Design. A systematic review was conducted to determine the effectiveness of multimodal exercise interventions on CRF. Databases of PubMed, CENTRAL, EMBASE, and OVID were searched between January and March 2014 to retrieve randomized controlled trials. Risk of bias was evaluated using the PEDro scale. Results. Nine studies (𝑛 = 772) were included in both systematic review and meta-analysis. Multimodal interventions including aerobic exercise, resistance training, and stretching improved CRF symptoms (SMD = −0.23; 95% CI: −0.37 to −0.09; 𝑃 = 0.001). These effects were also significant in patients undergoing chemotherapy (𝑃 < 0.0001). Nonsignificant differences were found for resistance training interventions(𝑃 = 0.30). Slight evidence of publication bias was observed (𝑃 = 0.04).The studies had a low risk of bias (PEDro scale mean score of 6.4 (standard deviation (SD) ± 1.0)). Conclusion. Supervised multimodal exercise interventions including aerobic, resistance, and stretching exercises are effective in controlling CRF. These findings suggest that these exercise protocols should be included as a crucial part of the rehabilitation programs for cancer survivors and patients during anticancer treatments.
format Desconocido (Unknown)
author Meneses-Echávez, José Francisco
González-Jiménez, Emilio
Ramírez-Vélez, Robinson
author_facet Meneses-Echávez, José Francisco
González-Jiménez, Emilio
Ramírez-Vélez, Robinson
author_sort Meneses-Echávez, José Francisco
title Effects of supervised multimodal exercise interventions on cancer-related fatigue: systematic review and meta-analysis of randomized controlled trials
title_short Effects of supervised multimodal exercise interventions on cancer-related fatigue: systematic review and meta-analysis of randomized controlled trials
title_full Effects of supervised multimodal exercise interventions on cancer-related fatigue: systematic review and meta-analysis of randomized controlled trials
title_fullStr Effects of supervised multimodal exercise interventions on cancer-related fatigue: systematic review and meta-analysis of randomized controlled trials
title_full_unstemmed Effects of supervised multimodal exercise interventions on cancer-related fatigue: systematic review and meta-analysis of randomized controlled trials
title_sort effects of supervised multimodal exercise interventions on cancer-related fatigue: systematic review and meta-analysis of randomized controlled trials
publishDate 2019
url http://hdl.handle.net/11634/20382
_version_ 1712104127816794112
spelling ir-11634-203822020-05-09T10:14:31Z Effects of supervised multimodal exercise interventions on cancer-related fatigue: systematic review and meta-analysis of randomized controlled trials Meneses-Echávez, José Francisco González-Jiménez, Emilio Ramírez-Vélez, Robinson Multimodal Exercise Interventions Meta-Analysis Cancer-Related Fatigue Effects Objective. Cancer-related fatigue (CRF) is the most common and devastating problem in cancer patients even after successful treatment. This study aimed to determine the effects of supervised multimodal exercise interventions on cancer-related fatigue through a systematic review and meta-analysis. Design. A systematic review was conducted to determine the effectiveness of multimodal exercise interventions on CRF. Databases of PubMed, CENTRAL, EMBASE, and OVID were searched between January and March 2014 to retrieve randomized controlled trials. Risk of bias was evaluated using the PEDro scale. Results. Nine studies (𝑛 = 772) were included in both systematic review and meta-analysis. Multimodal interventions including aerobic exercise, resistance training, and stretching improved CRF symptoms (SMD = −0.23; 95% CI: −0.37 to −0.09; 𝑃 = 0.001). These effects were also significant in patients undergoing chemotherapy (𝑃 < 0.0001). Nonsignificant differences were found for resistance training interventions(𝑃 = 0.30). Slight evidence of publication bias was observed (𝑃 = 0.04).The studies had a low risk of bias (PEDro scale mean score of 6.4 (standard deviation (SD) ± 1.0)). Conclusion. Supervised multimodal exercise interventions including aerobic, resistance, and stretching exercises are effective in controlling CRF. 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