The pamoras, their utilitites and advances in the treatment of side effects opiod on mu receptors

The aim of this paper is to review the state of knowledge of the utilities of the Pamoras in treating the collateral ef- fects of opioids with mu receptors. We searched the scientific literature between the years 2001-2010 from which we conclude that Pamoras, particularly methylnaltrexone and alvimo...

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Detalles Bibliográficos
Autores Principales: Daza Barriga, Jorge, Ruiz Pérez, Ornella
Formato: http://purl.org/coar/resource_type/c_6501
Lenguaje:Español (Spanish)
Publicado: Universidad Libre 2011
Acceso en línea:http://hdl.handle.net/10901/14737
Descripción
Sumario:The aim of this paper is to review the state of knowledge of the utilities of the Pamoras in treating the collateral ef- fects of opioids with mu receptors. We searched the scientific literature between the years 2001-2010 from which we conclude that Pamoras, particularly methylnaltrexone and alvimopan have proved useful in the treatment of gastrointestinal effects, to the extent that its use has been approved by the Food and Drug Administration. Prob- ably other undesirable effects of opioids such as urinary retention, nausea and itching may also be treated with these substances, but additional research is needed. In addition, intensively studied the effects of actions on other cellular pamoras undesirable opiates, such as tumor growth and increased vascular permeability. The actions are mediated primarily by peripheral mu receptor antagonism.