Aspectos farmacogeneticos del mtx, en un grupo de pacientes colombianos con artritis reumatoide.

20 páginas

Detalles Bibliográficos
Autores Principales: Saldarriaga Cardeno, Eugenia Lucia, Ospina, María José
Otros Autores: Santos, Pedro
Formato: Desconocido (Unknown)
Lenguaje:Español (Spanish)
Publicado: Universidad de La Sabana 2019
Materias:
Acceso en línea:http://hdl.handle.net/10818/34940
id ir-10818-34940
recordtype dspace
institution Universidad de La Sabana
collection DSpace
language Español (Spanish)
topic Metotrexato
Artritis reumatoide
Polimorfismo de nucleótido simple
spellingShingle Metotrexato
Artritis reumatoide
Polimorfismo de nucleótido simple
Saldarriaga Cardeno, Eugenia Lucia
Ospina, María José
Aspectos farmacogeneticos del mtx, en un grupo de pacientes colombianos con artritis reumatoide.
description 20 páginas
author2 Santos, Pedro
author_facet Santos, Pedro
Saldarriaga Cardeno, Eugenia Lucia
Ospina, María José
format Desconocido (Unknown)
author Saldarriaga Cardeno, Eugenia Lucia
Ospina, María José
author_sort Saldarriaga Cardeno, Eugenia Lucia
title Aspectos farmacogeneticos del mtx, en un grupo de pacientes colombianos con artritis reumatoide.
title_short Aspectos farmacogeneticos del mtx, en un grupo de pacientes colombianos con artritis reumatoide.
title_full Aspectos farmacogeneticos del mtx, en un grupo de pacientes colombianos con artritis reumatoide.
title_fullStr Aspectos farmacogeneticos del mtx, en un grupo de pacientes colombianos con artritis reumatoide.
title_full_unstemmed Aspectos farmacogeneticos del mtx, en un grupo de pacientes colombianos con artritis reumatoide.
title_sort aspectos farmacogeneticos del mtx, en un grupo de pacientes colombianos con artritis reumatoide.
publisher Universidad de La Sabana
publishDate 2019
url http://hdl.handle.net/10818/34940
_version_ 1679480262793101312
spelling ir-10818-349402019-10-08T19:21:05Z Aspectos farmacogeneticos del mtx, en un grupo de pacientes colombianos con artritis reumatoide. Saldarriaga Cardeno, Eugenia Lucia Ospina, María José Santos, Pedro Briceño Balcázar, Ignacio Metotrexato Artritis reumatoide Polimorfismo de nucleótido simple 20 páginas El metotrexato (MTX) como monoterapia o en combinación es el medicamento modificador de la enfermedad (FARMES) más utilizado en el tratamiento de la artritis reumatoide (AR). Cerca del 40% de los pacientes presenta falla terapéutica o toxicidad; la variabilidad genética en las enzimas involucradas en la ruta metabólica del MTX podría influenciar este fenómeno. El objetivo de este estudio es determinar la presencia de polimorfismos de nucleótido simple de su sigla en inglés (SNPs) en las enzimas implicadas en el metabolismo del MTX y su relación con la respuesta terapéutica en un grupo de pacientes colombianos con diagnóstico de artritis reumatoide. 2019-02-11T16:53:17Z 2019-02-11T16:53:17Z 2018-02-28 bachelorThesis Santos AM, Rueda JC, Angarita JI, Giraldo R, Forero E, Pelaez-Ballestas I, Munoz JGB, Saldarriaga EL, Ramirez J, Toro C, Londono J. Prevalence of Rheumatic Disease in an Adult Population from Colombia. A COPCORD Methodology Study. Annals of the Rheumatic Diseases 2017;76:752-3. Anderson J, Caplan L, Yazdany J, Robbins ML, Neogi T, Michaud K, Saag KG, O'Dell JR, Kazi S. Rheumatoid arthritis disease activity measures: American College of Rheumatology recommendations for use in clinical practice. 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