Polyurethane-based bioadhesive synthesized from polyols derived from castor oil (Ricinus communis) and low concentration of chitosan
12 páginas
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Journal of Materials Research
5/21
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Acceso en línea: | http://hdl.handle.net/10818/32969 |
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ir-10818-329692022-05-19T19:19:57Z Polyurethane-based bioadhesive synthesized from polyols derived from castor oil (Ricinus communis) and low concentration of chitosan Uscátegui, Yomaira L. Arévalo Alquichire, Said José Gómez Tejedor, José Antonio Vallés-Lluch, Ana Díaz Barrera, Luis Eduardo Valero Valdivieso, Manuel Fernando Adhesion Biomedical devices Chemical reaction 12 páginas Polyurethane-based bioadhesive was synthesized with polyols derived from castor oil (chemically modified and unmodified) and hexamethylene diisocyanate with chitosan addition as a bioactive filler. The objective was to evaluate the effect of type of polyols with the incorporation of low-concentrations of chitosan on the mechanical and biological properties of the polymer to obtain suitable materials in the design of biomaterials. The results showed that increasing physical crosslinking increased the mechanical and adhesive properties. An in vitro cytotoxic test of polyurethanes showed cellular viability. The biocompatibility of the polyurethanes favors the adhesion of L929 cells at 6, 24, and 48 h. The polyurethanes showed bacterial inhibition depending on the polyol and percentage of chitosan. The antibacterial effect of the polyurethanes for Escherichia coli decreased 60–90% after 24 h. The mechanical and adhesive properties together with biological response in this research suggested these polyurethanes as external application tissue bioadhesives. 5/21/2018 9:26 5/21/2018 9:26 2017-09-25 journal article publishedVersion Uscátegui, Y., Arévalo-Alquichire, S., Gómez-Tejedor, J., Vallés-Lluch, A., Díaz, L., & Valero, M. (2017). Polyurethane-based bioadhesive synthesized from polyols derived from castor oil (Ricinus communis) and low concentration of chitosan. Journal of Materials Research, 32(19), 3699-3711. doi:10.1557/jmr.2017.371 0884-2914 https://www.researchgate.net/publication/320022492_Polyurethane-based_bioadhesive_synthesized_from_polyols_derived_from_castor_oil_Ricinus_communis_and_low_concentration_of_chitosan http://hdl.handle.net/10818/32969 eng Journal of Materials Research 32(19):1-13 Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/ openAccess application/pdf Journal of Materials Research Universidad de La Sabana Intellectum Repositorio Universidad de La Sabana Universidad de La Sabana Intellectum Repositorio Universidad de La Sabana https://intellectum.unisabana.edu.co |
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Universidad de La Sabana |
collection |
DSpace |
language |
Inglés (English) |
topic |
Adhesion Biomedical devices Chemical reaction |
spellingShingle |
Adhesion Biomedical devices Chemical reaction Uscátegui, Yomaira L. Arévalo Alquichire, Said José Gómez Tejedor, José Antonio Vallés-Lluch, Ana Díaz Barrera, Luis Eduardo Valero Valdivieso, Manuel Fernando Polyurethane-based bioadhesive synthesized from polyols derived from castor oil (Ricinus communis) and low concentration of chitosan |
description |
12 páginas |
format |
journal article |
author |
Uscátegui, Yomaira L. Arévalo Alquichire, Said José Gómez Tejedor, José Antonio Vallés-Lluch, Ana Díaz Barrera, Luis Eduardo Valero Valdivieso, Manuel Fernando |
author_facet |
Uscátegui, Yomaira L. Arévalo Alquichire, Said José Gómez Tejedor, José Antonio Vallés-Lluch, Ana Díaz Barrera, Luis Eduardo Valero Valdivieso, Manuel Fernando |
author_sort |
Uscátegui, Yomaira L. |
title |
Polyurethane-based bioadhesive synthesized from polyols derived from castor oil (Ricinus communis) and low concentration of chitosan |
title_short |
Polyurethane-based bioadhesive synthesized from polyols derived from castor oil (Ricinus communis) and low concentration of chitosan |
title_full |
Polyurethane-based bioadhesive synthesized from polyols derived from castor oil (Ricinus communis) and low concentration of chitosan |
title_fullStr |
Polyurethane-based bioadhesive synthesized from polyols derived from castor oil (Ricinus communis) and low concentration of chitosan |
title_full_unstemmed |
Polyurethane-based bioadhesive synthesized from polyols derived from castor oil (Ricinus communis) and low concentration of chitosan |
title_sort |
polyurethane-based bioadhesive synthesized from polyols derived from castor oil (ricinus communis) and low concentration of chitosan |
publisher |
Journal of Materials Research |
publishDate |
5/21 |
url |
http://hdl.handle.net/10818/32969 |
_version_ |
1741873587623559168 |
score |
12,131701 |