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Trans-Ancestral Studies Fine Map the SLE-Susceptibility Locus TNFSF4

We previously established an 80 kb haplotype upstream of TNFSF4 as a susceptibility locus in the autoimmune disease SLE. SLE-associated alleles at this locus are associated with inflammatory disorders, including atherosclerosis and ischaemic stroke. In Europeans, the TNFSF4 causal variants have rema...

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Detalles Bibliográficos
Autores Principales: Manku, Harinder, Langefeld, Carl D., Guerra, Sandra G., Malik, Talat H., Alarcón-Riquelme, Marta E., Anaya, Juan-Manuel, Bae, Sang-Cheol, Boackle, Susan, Brown, Elizabeth E., Criswell, Lindsey A., Freedman, Barry I., Gaffney, Patrick M., Gregersen, Peter A., Guthridge, Joel M., Han, Sang-Hoon, Harley, John B., Jacob, Chaim O., James, Judith A., Kamen, Diane L., Kaufman, Kenneth M., Kelly, Jennifer A., Martin, Javier, Merrill, Joan T., Moser, Kathy L., Niewold, Timothy B., Park, So-Yeon, Pons-Estel, Bernardo A., Sawalha, Amr H., Scofield, Robert H., Shen, Nan, Stevens, Anne M., Sun, Celi, Gilkeson, Gary S., Edberg, Jeffrey C., Kimberly, Robert P., Nath, Swapan K., Tsao, Betty P., Vyse, Timothy J.
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: Universidad del Rosario 2013
Materias:
Evolución & genética
Autoantibody
OX40 ligand
Transcription factor RelA
African American
Allele
American Indian
Antibody production
Cell isolation
Anticuerpos
Alelos
Genética
Inmunología
Acceso en línea:http://repository.urosario.edu.co/handle/10336/8829
https://doi.org/10.1371/journal.pgen.1003554

Internet

http://repository.urosario.edu.co/handle/10336/8829
https://doi.org/10.1371/journal.pgen.1003554

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