3D Analysis of the TCR/pMHCII Complex Formation in Monkeys Vaccinated with the First Peptide Inducing Sterilizing Immunity against Human Malaria

T-cell receptor gene rearrangements were studied in Aotus monkeys developing high antibody titers and sterilizing immunity against the Plasmodium falciparum malaria parasite upon vaccination with the modified synthetic peptide 24112, which was identified in the Merozoite Surface Protein 2 (MSP-2) an...

Descripción completa

Detalles Bibliográficos
Autores Principales: Patarroyo, Manuel A., Bermudez, Adriana, López, Carolina, Yepes, Gloria, Patarroyo, Manuel E.
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: Universidad del Rosario 2010
Materias:
Acceso en línea:http://repository.urosario.edu.co/handle/10336/8806
https://doi.org/10.1371/journal.pone.0009771