Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility
Systemic lupus erythematosus (SLE), a complex polygenic autoimmune disease, is associated with increased complement activation. Variants of genes encoding complement regulator factor H (CFH) and five CFH-related proteins (CFHR1-CFHR5) within the chromosome 1q32 locus linked to SLE, have been associa...
Autores Principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Artículo (Article) |
Lenguaje: | Inglés (English) |
Publicado: |
Universidad del Rosario
2011
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Materias: | |
Acceso en línea: | http://repository.urosario.edu.co/handle/10336/8779 https://doi.org/10.1371/journal.pgen.1002079 |