Genome-Wide Linkage in a Highly Consanguineous Pedigree Reveals Two Novel Loci on Chromosome 7 for Non-Syndromic Familial Premature Ovarian Failure

Background: The human condition known as Premature Ovarian Failure (POF) is characterized by loss of ovarian function before the age of 40. A majority of POF cases are sporadic, but 10–15% are familial, suggesting a genetic origin of the disease. Although several causal mutations have been identifie...

Descripción completa

Detalles Bibliográficos
Autores Principales: Caburet, Sandrine, Zavadakova, Petra, Ben-Neriah, Ziva, Bouhali, Kamal, Dipietromaria, Aurélie, Charon, Céline, Besse, Céline, Laissue, Paul, Chalifa-Caspi, Vered, Christin-Maitre, Sophie, Vaiman, Daniel, Levi, Giovanni, Veitia, Reiner, Fellous, Marc
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: Universidad del Rosario 2012
Materias:
Acceso en línea:http://repository.urosario.edu.co/handle/10336/8769