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PTPN22 Association in Systemic Lupus Erythematosus (SLE) with Respect to Individual Ancestry and Clinical Sub-Phenotypes

Protein tyrosine phosphatase non-receptor type 22 (PTPN22) is a negative regulator of T-cell activation associated with several autoimmune diseases, including systemic lupus erythematosus (SLE). Missense rs2476601 is associated with SLE in individuals with European ancestry. Since the rs2476601 risk...

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Detalles Bibliográficos
Autores Principales: Namjou, Bahram, Kim-Howard, Xana, Sun, Celi, Adler, Adam, Chung, Sharon, Kaufman, Kenneth M., Kelly, Jennifer A., Glenn, Stuart B., Guthridge, Joel M., Scofield, Robert H., Kimberly, Robert P., Brown, Elizabeth E., Alarcón, Graciela S., Edberg, Jeffrey C., Kim, Jae-Hoon, Choi, Jiyoung, Ramsey-Goldman, Rosalind, Petri, Michelle A., Reveille, John D., Vilá, Luis M., Boackle, Susan, Freedman, Barry I., Tsao, Betty P., Langefeld, Carl D., Vyse, Timothy J., Jacob, Chaim O., Pons-Estel, Bernardo A., Niewold, Timothy B., Moser Sivils, Kathy, Merrill, Joan T., Anaya, Juan-Manuel, Gilkeson, Gary S., Gaffney, Patrick M., Bae, Sang-Cheol, Alarcón-Riquelme, Marta E., Harley, John B., Criswell, Lindsey A., James, Judith A., Nath, Swapan K.
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: Universidad del Rosario 2013
Materias:
Enfermedades
Arthritis and Clinical Immunology Research Program
University of Texas Health Science Center at Houston
Cincinnati Children’s Hospital Medical Center
Johns Hopkins University School of Medicine
Northwestern University Feinberg School of Medicine
Oklahoma Medical Research Foundation
Rosalind Russell Medical Research Center for Arthritis
US Department of Veterans Affairs Medical Center
University of Oklahoma Health Sciences Center
University of Alabama at Birmingham
Division of Rheumatology
Department of Medicine
Department of Internal Medicine
University of Puerto Rico Medical Sciences Campus
Lupus eritematoso sistémico
PTPN22
Inmunología
Acceso en línea:http://repository.urosario.edu.co/handle/10336/8763
https://doi.org/10.1371/journal.pone.0069404

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