PTPN22 Association in Systemic Lupus Erythematosus (SLE) with Respect to Individual Ancestry and Clinical Sub-Phenotypes

Protein tyrosine phosphatase non-receptor type 22 (PTPN22) is a negative regulator of T-cell activation associated with several autoimmune diseases, including systemic lupus erythematosus (SLE). Missense rs2476601 is associated with SLE in individuals with European ancestry. Since the rs2476601 risk...

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Detalles Bibliográficos
Autores Principales: Namjou, Bahram, Kim-Howard, Xana, Sun, Celi, Adler, Adam, Chung, Sharon, Kaufman, Kenneth M., Kelly, Jennifer A., Glenn, Stuart B., Guthridge, Joel M., Scofield, Robert H., Kimberly, Robert P., Brown, Elizabeth E., Alarcón, Graciela S., Edberg, Jeffrey C., Kim, Jae-Hoon, Choi, Jiyoung, Ramsey-Goldman, Rosalind, Petri, Michelle A., Reveille, John D., Vilá, Luis M., Boackle, Susan, Freedman, Barry I., Tsao, Betty P., Langefeld, Carl D., Vyse, Timothy J., Jacob, Chaim O., Pons-Estel, Bernardo A., Niewold, Timothy B., Moser Sivils, Kathy, Merrill, Joan T., Anaya, Juan-Manuel, Gilkeson, Gary S., Gaffney, Patrick M., Bae, Sang-Cheol, Alarcón-Riquelme, Marta E., Harley, John B., Criswell, Lindsey A., James, Judith A., Nath, Swapan K.
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: Universidad del Rosario 2013
Materias:
Acceso en línea:http://repository.urosario.edu.co/handle/10336/8763