Molecular mechanism involved in the mutagenicity induced by Aflatoxin B1

The aflatoxin B1 (AFB1) is a mycotoxin that has been identified as the most potent hepatocarcinogen. The metabolite resulting from detoxification process of AFB1 in liver, has the ability to react with the genomic DNA, generating AFB1-DNA adducts; during DNA replication process, this adduct induced...

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Detalles Bibliográficos
Autor Principal: Uribe-Yunda, Diego-Fernando
Formato: Artículo (Article)
Lenguaje:Español (Spanish)
Publicado: Universidad del Rosario 2012
Materias:
Acceso en línea:http://revistas.urosario.edu.co/index.php/revsalud/article/view/2302
http://repository.urosario.edu.co/handle/10336/7611