Characterization of resistance in vitro to different antimicrobial in strains of Staphylococcus spp. in a hospital of the city of Valledupar between January and July 2009

The Staphylococcus spp. they can cause a wide range of infections systemic and located in community and hospital patients. Its high pathogenicity and growing resistance to multiple antimicrobials including methicillin, causes high morbiditymortality rates, causing a high epidemiological impact. Obje...

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Autores Principales: Morales, Gloria Inés, Yaneth, María Cecilia, Chávez, Katiuska
Formato: Artículo (Article)
Lenguaje:Español (Spanish)
Publicado: Universidad del Rosario 2012
Materias:
Acceso en línea:http://revistas.urosario.edu.co/index.php/revsalud/article/view/2178
http://repository.urosario.edu.co/handle/10336/7415
id ir-10336-7415
recordtype dspace
institution EdocUR - Universidad del Rosario
collection DSpace
language Español (Spanish)
topic bacterial resistance; MRS; Staphylococcus aureus
resistencia bacteriana; MRS; Staphylococcus aureus
resistência bacteriana; MRS; Staphylococcus aureus
spellingShingle bacterial resistance; MRS; Staphylococcus aureus
resistencia bacteriana; MRS; Staphylococcus aureus
resistência bacteriana; MRS; Staphylococcus aureus
Morales, Gloria Inés
Yaneth, María Cecilia
Chávez, Katiuska
Characterization of resistance in vitro to different antimicrobial in strains of Staphylococcus spp. in a hospital of the city of Valledupar between January and July 2009
description The Staphylococcus spp. they can cause a wide range of infections systemic and located in community and hospital patients. Its high pathogenicity and growing resistance to multiple antimicrobials including methicillin, causes high morbiditymortality rates, causing a high epidemiological impact. Objective: to determine the phenotypic profile of resistance to different antimicrobials in strains of the genus Staphylococcus spp. Materials and methods: collected 75 strains and determined them susceptibility to different antibiotics by the Kirby-Bauer method. The production of betalactamasecheck using the nitrocefin test. (Resistance to Methicillin in S. aureus was conductedusing Mueller Hinton with 4% NaCl and oxacillin 6 μg/mL). Inducible clindamycin resistance tamizo by D-Test test. Results: they were isolated by 38% of staphylococcus coagulase negative (SNA) and 62% of S. aureus. 53% were penicillin resistant staphylococci: S. aureus with 58% and 42% SNA. 47% of the strains showed resistance to methicillin: S. aureus with 61% and SNA with 39%. A strain of S. aureus showed inducible resistance to clindamycin (1.33%). Coagulase negative staphylococci were isolated mostly from blood samples (31%), blood (29%), tip of catheter (5%) and came mostly from neonatal ICU (25%), medical (21%) and surgery (16%).Conclusions: S. aureus and SNA were isolated with greater frequency in blood and wounds from surgery and neonatal ICU. The predominant resistance phenotypes were penicillin and oxacillin.
format Artículo (Article)
author Morales, Gloria Inés
Yaneth, María Cecilia
Chávez, Katiuska
author_facet Morales, Gloria Inés
Yaneth, María Cecilia
Chávez, Katiuska
author_sort Morales, Gloria Inés
title Characterization of resistance in vitro to different antimicrobial in strains of Staphylococcus spp. in a hospital of the city of Valledupar between January and July 2009
title_short Characterization of resistance in vitro to different antimicrobial in strains of Staphylococcus spp. in a hospital of the city of Valledupar between January and July 2009
title_full Characterization of resistance in vitro to different antimicrobial in strains of Staphylococcus spp. in a hospital of the city of Valledupar between January and July 2009
title_fullStr Characterization of resistance in vitro to different antimicrobial in strains of Staphylococcus spp. in a hospital of the city of Valledupar between January and July 2009
title_full_unstemmed Characterization of resistance in vitro to different antimicrobial in strains of Staphylococcus spp. in a hospital of the city of Valledupar between January and July 2009
title_sort characterization of resistance in vitro to different antimicrobial in strains of staphylococcus spp. in a hospital of the city of valledupar between january and july 2009
publisher Universidad del Rosario
publishDate 2012
url http://revistas.urosario.edu.co/index.php/revsalud/article/view/2178
http://repository.urosario.edu.co/handle/10336/7415
_version_ 1645141183354109952
spelling ir-10336-74152019-09-19T12:37:01Z Characterization of resistance in vitro to different antimicrobial in strains of Staphylococcus spp. in a hospital of the city of Valledupar between January and July 2009 Caracterización de la resistencia in vitro a diferentes antimicrobianos en cepas de Staphylococcus spp. en una institución hospitalaria de la ciudad de Valledupar entre enero y julio de 2009 Caracterização da resistência in vitro a diferentes antimicrobianos em cepas de Staphylococcus spp. em uma instituição hospitalaria da cidade de Valledupar entre janeiro y julho de 2009 Morales, Gloria Inés Yaneth, María Cecilia Chávez, Katiuska bacterial resistance; MRS; Staphylococcus aureus resistencia bacteriana; MRS; Staphylococcus aureus resistência bacteriana; MRS; Staphylococcus aureus The Staphylococcus spp. they can cause a wide range of infections systemic and located in community and hospital patients. Its high pathogenicity and growing resistance to multiple antimicrobials including methicillin, causes high morbiditymortality rates, causing a high epidemiological impact. Objective: to determine the phenotypic profile of resistance to different antimicrobials in strains of the genus Staphylococcus spp. Materials and methods: collected 75 strains and determined them susceptibility to different antibiotics by the Kirby-Bauer method. The production of betalactamasecheck using the nitrocefin test. (Resistance to Methicillin in S. aureus was conductedusing Mueller Hinton with 4% NaCl and oxacillin 6 μg/mL). Inducible clindamycin resistance tamizo by D-Test test. Results: they were isolated by 38% of staphylococcus coagulase negative (SNA) and 62% of S. aureus. 53% were penicillin resistant staphylococci: S. aureus with 58% and 42% SNA. 47% of the strains showed resistance to methicillin: S. aureus with 61% and SNA with 39%. A strain of S. aureus showed inducible resistance to clindamycin (1.33%). Coagulase negative staphylococci were isolated mostly from blood samples (31%), blood (29%), tip of catheter (5%) and came mostly from neonatal ICU (25%), medical (21%) and surgery (16%).Conclusions: S. aureus and SNA were isolated with greater frequency in blood and wounds from surgery and neonatal ICU. The predominant resistance phenotypes were penicillin and oxacillin. Los Staphylococcus spp. causan un amplio rango de infecciones sistémicas y localizadas en pacientes hospitalizados y comunitarios. Su alta patogenicidad y su creciente resistencia a múltiples antimicrobianos, entre ellos la meticilina, provocan elevadas tasas de morbimortalidad ocasionando un alto impacto epidemiológico. Objetivo: determinar el perfil fenotípico de resistencia a diferentes antimicrobianos en cepas del género Staphylococcus spp. Materiales y métodos: se recolectaron setenta y cinco cepas y se determinó susceptibilidad a diferentes antibióticos por el método de Kirby Bauer. La producción de beta-lactamasa se verificó mediante la prueba del nitrocefin. La resistencia a lameticilina en S. aureus se realizó usando Mueller Hinton con 4% de NaCl y oxacilina 6 μg/mL. La resistencia inducible a clindamicina se tamizó mediante la prueba del D-Test. Resultados: se aisló un 38% de estafilococos coagulasa negativa (SCN) y un 62% de S. aureus. Un 53% de los estafilococos fueron resistentes a penicilina: S. aureus con 58% y SCN 42%; un 47% de las cepas presentaron resistencia a meticilina: S. aureus con un 61% y SCN con un 39%; una cepa de S. aureus mostró resistencia inducible a la clindamicina (1,33%). En su mayoría, los estafilococos coagulasa negativa fueron aislados a partir de muestras de hemocultivos (31%) y los estafilococos meticilino-resistentes predominaron en muestras de heridas (46%), hemocultivo (29%) y punta de catéter (5%); gran parte de ellos procedía de UCI neonatal (25%), médica (21%) y cirugía (16%). Conclusiones: S.aureus y SCN se aislaron con mayor frecuencia en hemocultivos y heridas procedentes de UCI neonatal y cirugía. Los fenotipos de resistencia predominantes fueron para penicilina y oxacilina. Os Staphylococcus spp. causam uma ampla série de infecções sistemáticas e localizadas em pacientes hospitalizados e comunitários. Sua alta patogenicidade e sua crescente resistência a múltiplosantimicrobianos, entre eles a meticilina, causam taxas elevadas de morbimortalidade ocasionandoum alto impacto epidemiológico. Objetivo: determinar o perfil fenotípico de resistência a diferentes antimicrobianos em cepas do gênero Staphylococcus spp. Materiais e métodos: se recoletaram setentae cinco cepas, e determinou-se suscetibilidade aos diferentes antibióticos pelo método de KirbyBauer. A produção de beta-lactamase verificou-se mediante a prova do nitrocefin. A resistência àmeticilina en S. aureus realizou-se usando Mueller Hinton com 4% de NaCl e oxacilina 6 μg/mL. A resistência induzível a clindamicina se tamisou mediante a prova do D-Test. Resultados: se isolo um38% de estafilococos coagulase negativa (SCN) e um 62% de S. aureus. Um 53% dos estafilococosforam resistentes à penicilina: S. aureus com 58% e SCN 42%; um 47% das cepas apresentaram resistência à meticilina: S. aureus com um 61% e SCN com um 39%; uma cepa de S. aureus mostrou resistência induzível á clindamicina (1,33%). Em sua maioria, os estafilococos coagulase negativa foram isolados a partir de amostras de hemoculturas (31%) e os estafilococos meticilino-resistentes predominaram em amostras de feridas (46%), hemocultura (29%) e ponta de cateter (5%); grande parte deles procedia de UCI neonatal (25%), médica (21%) e cirurgia (16%). Conclusões: S. aureusy SCN se isolaram com maior frequência em hemoculturas e feridas procedentes de UCI neonatale cirurgia. Os fenótipos de resistência predominantes foram para penicilina e oxacilina. 2012-08-31 2012-08-31 2014-07-09T15:55:59Z info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://revistas.urosario.edu.co/index.php/revsalud/article/view/2178 http://repository.urosario.edu.co/handle/10336/7415 spa http://creativecommons.org/licenses/by-nc/4.0 info:eu-repo/semantics/openAccess application/pdf Universidad del Rosario instname:Universidad del Rosario reponame:Repositorio Institucional EdocUR Revista Ciencias de la Salud; Vol. 10, núm. 2 (2012); 5-13 Revista Ciencias de la Salud; Vol. 10, núm. 2 (2012); 5-13 Revista Ciencias de la Salud; Vol. 10, núm. 2 (2012); 5-13 2145-4507 1692-7273
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