Comparación de la severidad y extensión de la enfermedad coronaria multivaso por Syntax Score en una poblaciòn de las Antillas Holandesas vs controles nacionales

En la Enfermedad Coronaria (EC) existen factores genéticos, socioculturales, medioambientales y raciales adicionales a los factores de riesgo cardiovascular mayores que podrían influir en su presentación. Se desconoce el impacto de la raza en la severidad de la enfermedad coronaria en los pacientes...

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Autores Principales: Medina Lòpez, Libardo Augusto, Gil Aldana, Victor José
Otros Autores: Echeverri Arcila, Darío
Formato: Trabajo de grado (Bachelor Thesis)
Lenguaje:Español (Spanish)
Publicado: Universidad del Rosario 2012
Materias:
Acceso en línea:http://repository.urosario.edu.co/handle/10336/3617
id ir-10336-3617
recordtype dspace
institution EdocUR - Universidad del Rosario
collection DSpace
language Español (Spanish)
topic Enfermedad coronaria
Syntax Score
Enfermedad coronaria::Investigaciones
Traumatismos cardiacos::Investigaciones
Cardiología::Investigaciones
Coronary artery disease
Score Syntax
spellingShingle Enfermedad coronaria
Syntax Score
Enfermedad coronaria::Investigaciones
Traumatismos cardiacos::Investigaciones
Cardiología::Investigaciones
Coronary artery disease
Score Syntax
Medina Lòpez, Libardo Augusto
Gil Aldana, Victor José
Comparación de la severidad y extensión de la enfermedad coronaria multivaso por Syntax Score en una poblaciòn de las Antillas Holandesas vs controles nacionales
description En la Enfermedad Coronaria (EC) existen factores genéticos, socioculturales, medioambientales y raciales adicionales a los factores de riesgo cardiovascular mayores que podrían influir en su presentación. Se desconoce el impacto de la raza en la severidad de la enfermedad coronaria en los pacientes extranjeros que son enviados a nuestro Servicio. Objetivos: Comparar la severidad de la EC multivaso en una población de pacientes de las Antillas y Nacionales, pareados por la escala Framingham. Metodología: Realizamos un estudio de corte transversal, comparando pacientes colombianos contra pacientes provenientes de las Antillas holandesas con similares factores de riesgo según escala de Framingham, catalogándolos por grupos de riesgo bajo, intermedio, alto y muy alto. Todos con EC severa multivaso documentada por angiografía coronaria desde enero del 2009 hasta Junio de 2011. Se excluyeron pacientes con antecedentes de intervención percutánea o quirúrgica previa. Resultados: Ingresaron 115 pacientes internacionales y 115 pacientes nacionales. La relación hombres/mujeres 3:1. La proporción de grupos de riesgo fue de bajo riesgo 2.5%, intermedio 15%, alto 19.3%, y muy alto 63.4%. El Syntax Score en pacientes nacionales fue 14.3+/-7.4 y en internacionales 22.2+/-10.5 p: 0.002. Conclusiones: En pacientes provenientes de las Antillas Holandesas, valorados en nuestra institución, se observó una mayor severidad de la enfermedad coronaria comparada con una población nacional con factores de riesgo similares. Estos hallazgos sugieren la influencia de la raza y factores genéticos en la severidad y extensión de la EC
author2 Echeverri Arcila, Darío
author_facet Echeverri Arcila, Darío
Medina Lòpez, Libardo Augusto
Gil Aldana, Victor José
format Trabajo de grado (Bachelor Thesis)
author Medina Lòpez, Libardo Augusto
Gil Aldana, Victor José
author_sort Medina Lòpez, Libardo Augusto
title Comparación de la severidad y extensión de la enfermedad coronaria multivaso por Syntax Score en una poblaciòn de las Antillas Holandesas vs controles nacionales
title_short Comparación de la severidad y extensión de la enfermedad coronaria multivaso por Syntax Score en una poblaciòn de las Antillas Holandesas vs controles nacionales
title_full Comparación de la severidad y extensión de la enfermedad coronaria multivaso por Syntax Score en una poblaciòn de las Antillas Holandesas vs controles nacionales
title_fullStr Comparación de la severidad y extensión de la enfermedad coronaria multivaso por Syntax Score en una poblaciòn de las Antillas Holandesas vs controles nacionales
title_full_unstemmed Comparación de la severidad y extensión de la enfermedad coronaria multivaso por Syntax Score en una poblaciòn de las Antillas Holandesas vs controles nacionales
title_sort comparación de la severidad y extensión de la enfermedad coronaria multivaso por syntax score en una poblaciòn de las antillas holandesas vs controles nacionales
publisher Universidad del Rosario
publishDate 2012
url http://repository.urosario.edu.co/handle/10336/3617
_version_ 1645142020318035968
spelling ir-10336-36172019-09-19T12:37:01Z Comparación de la severidad y extensión de la enfermedad coronaria multivaso por Syntax Score en una poblaciòn de las Antillas Holandesas vs controles nacionales Medina Lòpez, Libardo Augusto Gil Aldana, Victor José Echeverri Arcila, Darío Enfermedad coronaria Syntax Score Enfermedad coronaria::Investigaciones Traumatismos cardiacos::Investigaciones Cardiología::Investigaciones Coronary artery disease Score Syntax En la Enfermedad Coronaria (EC) existen factores genéticos, socioculturales, medioambientales y raciales adicionales a los factores de riesgo cardiovascular mayores que podrían influir en su presentación. Se desconoce el impacto de la raza en la severidad de la enfermedad coronaria en los pacientes extranjeros que son enviados a nuestro Servicio. Objetivos: Comparar la severidad de la EC multivaso en una población de pacientes de las Antillas y Nacionales, pareados por la escala Framingham. Metodología: Realizamos un estudio de corte transversal, comparando pacientes colombianos contra pacientes provenientes de las Antillas holandesas con similares factores de riesgo según escala de Framingham, catalogándolos por grupos de riesgo bajo, intermedio, alto y muy alto. Todos con EC severa multivaso documentada por angiografía coronaria desde enero del 2009 hasta Junio de 2011. Se excluyeron pacientes con antecedentes de intervención percutánea o quirúrgica previa. Resultados: Ingresaron 115 pacientes internacionales y 115 pacientes nacionales. La relación hombres/mujeres 3:1. La proporción de grupos de riesgo fue de bajo riesgo 2.5%, intermedio 15%, alto 19.3%, y muy alto 63.4%. El Syntax Score en pacientes nacionales fue 14.3+/-7.4 y en internacionales 22.2+/-10.5 p: 0.002. Conclusiones: En pacientes provenientes de las Antillas Holandesas, valorados en nuestra institución, se observó una mayor severidad de la enfermedad coronaria comparada con una población nacional con factores de riesgo similares. Estos hallazgos sugieren la influencia de la raza y factores genéticos en la severidad y extensión de la EC Coronary artery disease (CAD) is still the first cause of morbidity and mortality in the general population. CAD has genetic, social, cultural, environmental and race backgroundsbesides the traditional major risks factors. It is unknown the impact of race in CAD´s severity within patients from Netherland Antilles, frequently referred to our service. Purpose:To compare the severity and extension of multivessel coronary artery disease by SYNTAX score between patients from Netherland Antilles vs Colombian patients after matching by Framingham Score Materials and Methods: We carried out a transversal cross sectional study by comparing patients from the Netherland Antilles vs Colombian patients after matching by Framingham Score in four categories (low risk, intermediate risk, high risk and very high risk). The patients correspond to those having multivessel coronary artery disease diagnosed by coronary angiography between January 2009 to June 2011. Results: 115 Colombian patients and 115 patients coming from the Netherland Antilles were included in this study, in a 3:1 ratio between females and males.. The proportion of patients belonging to several groups of risk where as follows: 2.5% low risk, 15% intermediate risk, 19.3% high risk, and 63.4% very high risk. The Syntax score for coronary artery disease was significantly higher among Caribbean from the Netherland Antilles (22.2+/-10.5) than among Colombians (14.3+/-7.4) p: 0.002. Conclusions: Patients coming from the Netherland Antilles had a higher severity index for coronary disease measured by angiography, after controlling for recognized risk factors. These findings support the notion that coronary disease is influenced by race, and genetic backgrounds. 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