Assessment of the Myogenic and Metabolic Mechanism Influence in Cerebral Autoregulation Using Near-Infrared Spectroscopy

Cerebral autoregulation is normally controlled via three different mechanisms, namely: the myogenic, the metabolic, and the neurogenic one. The myogenic mechanism responds efficiently to slow changes in mean arterial blood pressure (MABP) while the metabolic one is more efficient with fast changes....

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Autores Principales: Caicedo Dorado, Alexander, Naulaers, Gunnar, Wolf, Martin, Lemmers, Petra, Van Bel, Frank, Ameye, Lieveke, Van Huffel, Sabine Van
Formato: Capítulo de libro (Book Chapter)
Lenguaje:Inglés (English)
Publicado: Springer Nature 2011
Materias:
Acceso en línea:https://repository.urosario.edu.co/handle/10336/28880
https://doi.org/10.1007/978-1-4614-1566-4_6
id ir-10336-28880
recordtype dspace
spelling ir-10336-288802020-08-28T15:50:34Z Assessment of the Myogenic and Metabolic Mechanism Influence in Cerebral Autoregulation Using Near-Infrared Spectroscopy Evaluación de la influencia del mecanismo miogénico y metabólico en la autorregulación cerebral mediante espectroscopia de infrarrojo cercano Caicedo Dorado, Alexander Naulaers, Gunnar Wolf, Martin Lemmers, Petra Van Bel, Frank Ameye, Lieveke Van Huffel, Sabine Van Cerebral Blood Flow Mean Arterial Blood Pressure Cerebral Autoregulation Gain Score Metabolic Mechanism Cerebral autoregulation is normally controlled via three different mechanisms, namely: the myogenic, the metabolic, and the neurogenic one. The myogenic mechanism responds efficiently to slow changes in mean arterial blood pressure (MABP) while the metabolic one is more efficient with fast changes. The neurogenic mechanism is not yet well understood. As changes in cerebral intravascular oxygenation (HbD), measured with near-infrared spectroscopy (NIRS), reflect changes in cerebral blood flow, the myogenic influence in the cerebral autoregulation can be assessed by analysis of HbD and MABP; the metabolic influence can be assessed by analysis of the HbD and the partial pressure of carbon dioxide (pCO2). We performed a transfer function analysis in order to calculate the gain and phase of the HbD/MABP and HbD/PCO2 subsystems. Due to the fact that cerebral autoregulation may be absent in sick premature infants, we then investigated how well these parameters could predict clinical outcome in this population. 2011-11-10 2020-08-28T15:49:59Z info:eu-repo/semantics/bookPart info:eu-repo/semantics/publishedVersion ISBN: 978-1-4614-1565-7 https://repository.urosario.edu.co/handle/10336/28880 https://doi.org/10.1007/978-1-4614-1566-4_6 eng info:eu-repo/semantics/restrictedAccess application/pdf Springer Nature Advances in Experimental Medicine and Biology
institution EdocUR - Universidad del Rosario
collection DSpace
language Inglés (English)
topic Cerebral Blood Flow
Mean Arterial Blood Pressure
Cerebral Autoregulation
Gain Score
Metabolic Mechanism
spellingShingle Cerebral Blood Flow
Mean Arterial Blood Pressure
Cerebral Autoregulation
Gain Score
Metabolic Mechanism
Caicedo Dorado, Alexander
Naulaers, Gunnar
Wolf, Martin
Lemmers, Petra
Van Bel, Frank
Ameye, Lieveke
Van Huffel, Sabine Van
Assessment of the Myogenic and Metabolic Mechanism Influence in Cerebral Autoregulation Using Near-Infrared Spectroscopy
description Cerebral autoregulation is normally controlled via three different mechanisms, namely: the myogenic, the metabolic, and the neurogenic one. The myogenic mechanism responds efficiently to slow changes in mean arterial blood pressure (MABP) while the metabolic one is more efficient with fast changes. The neurogenic mechanism is not yet well understood. As changes in cerebral intravascular oxygenation (HbD), measured with near-infrared spectroscopy (NIRS), reflect changes in cerebral blood flow, the myogenic influence in the cerebral autoregulation can be assessed by analysis of HbD and MABP; the metabolic influence can be assessed by analysis of the HbD and the partial pressure of carbon dioxide (pCO2). We performed a transfer function analysis in order to calculate the gain and phase of the HbD/MABP and HbD/PCO2 subsystems. Due to the fact that cerebral autoregulation may be absent in sick premature infants, we then investigated how well these parameters could predict clinical outcome in this population.
format Capítulo de libro (Book Chapter)
author Caicedo Dorado, Alexander
Naulaers, Gunnar
Wolf, Martin
Lemmers, Petra
Van Bel, Frank
Ameye, Lieveke
Van Huffel, Sabine Van
author_facet Caicedo Dorado, Alexander
Naulaers, Gunnar
Wolf, Martin
Lemmers, Petra
Van Bel, Frank
Ameye, Lieveke
Van Huffel, Sabine Van
author_sort Caicedo Dorado, Alexander
title Assessment of the Myogenic and Metabolic Mechanism Influence in Cerebral Autoregulation Using Near-Infrared Spectroscopy
title_short Assessment of the Myogenic and Metabolic Mechanism Influence in Cerebral Autoregulation Using Near-Infrared Spectroscopy
title_full Assessment of the Myogenic and Metabolic Mechanism Influence in Cerebral Autoregulation Using Near-Infrared Spectroscopy
title_fullStr Assessment of the Myogenic and Metabolic Mechanism Influence in Cerebral Autoregulation Using Near-Infrared Spectroscopy
title_full_unstemmed Assessment of the Myogenic and Metabolic Mechanism Influence in Cerebral Autoregulation Using Near-Infrared Spectroscopy
title_sort assessment of the myogenic and metabolic mechanism influence in cerebral autoregulation using near-infrared spectroscopy
publisher Springer Nature
publishDate 2011
url https://repository.urosario.edu.co/handle/10336/28880
https://doi.org/10.1007/978-1-4614-1566-4_6
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score 11,384008