Assessment of the Myogenic and Metabolic Mechanism Influence in Cerebral Autoregulation Using Near-Infrared Spectroscopy
Cerebral autoregulation is normally controlled via three different mechanisms, namely: the myogenic, the metabolic, and the neurogenic one. The myogenic mechanism responds efficiently to slow changes in mean arterial blood pressure (MABP) while the metabolic one is more efficient with fast changes....
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2011
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Acceso en línea: | https://repository.urosario.edu.co/handle/10336/28880 https://doi.org/10.1007/978-1-4614-1566-4_6 |
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ir-10336-288802020-08-28T15:50:34Z Assessment of the Myogenic and Metabolic Mechanism Influence in Cerebral Autoregulation Using Near-Infrared Spectroscopy Evaluación de la influencia del mecanismo miogénico y metabólico en la autorregulación cerebral mediante espectroscopia de infrarrojo cercano Caicedo Dorado, Alexander Naulaers, Gunnar Wolf, Martin Lemmers, Petra Van Bel, Frank Ameye, Lieveke Van Huffel, Sabine Van Cerebral Blood Flow Mean Arterial Blood Pressure Cerebral Autoregulation Gain Score Metabolic Mechanism Cerebral autoregulation is normally controlled via three different mechanisms, namely: the myogenic, the metabolic, and the neurogenic one. The myogenic mechanism responds efficiently to slow changes in mean arterial blood pressure (MABP) while the metabolic one is more efficient with fast changes. The neurogenic mechanism is not yet well understood. As changes in cerebral intravascular oxygenation (HbD), measured with near-infrared spectroscopy (NIRS), reflect changes in cerebral blood flow, the myogenic influence in the cerebral autoregulation can be assessed by analysis of HbD and MABP; the metabolic influence can be assessed by analysis of the HbD and the partial pressure of carbon dioxide (pCO2). We performed a transfer function analysis in order to calculate the gain and phase of the HbD/MABP and HbD/PCO2 subsystems. Due to the fact that cerebral autoregulation may be absent in sick premature infants, we then investigated how well these parameters could predict clinical outcome in this population. 2011-11-10 2020-08-28T15:49:59Z info:eu-repo/semantics/bookPart info:eu-repo/semantics/publishedVersion ISBN: 978-1-4614-1565-7 https://repository.urosario.edu.co/handle/10336/28880 https://doi.org/10.1007/978-1-4614-1566-4_6 eng info:eu-repo/semantics/restrictedAccess application/pdf Springer Nature Advances in Experimental Medicine and Biology |
institution |
EdocUR - Universidad del Rosario |
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DSpace |
language |
Inglés (English) |
topic |
Cerebral Blood Flow Mean Arterial Blood Pressure Cerebral Autoregulation Gain Score Metabolic Mechanism |
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Cerebral Blood Flow Mean Arterial Blood Pressure Cerebral Autoregulation Gain Score Metabolic Mechanism Caicedo Dorado, Alexander Naulaers, Gunnar Wolf, Martin Lemmers, Petra Van Bel, Frank Ameye, Lieveke Van Huffel, Sabine Van Assessment of the Myogenic and Metabolic Mechanism Influence in Cerebral Autoregulation Using Near-Infrared Spectroscopy |
description |
Cerebral autoregulation is normally controlled via three different mechanisms, namely: the myogenic, the metabolic, and the neurogenic one. The myogenic mechanism responds efficiently to slow changes in mean arterial blood pressure (MABP) while the metabolic one is more efficient with fast changes. The neurogenic mechanism is not yet well understood. As changes in cerebral intravascular oxygenation (HbD), measured with near-infrared spectroscopy (NIRS), reflect changes in cerebral blood flow, the myogenic influence in the cerebral autoregulation can be assessed by analysis of HbD and MABP; the metabolic influence can be assessed by analysis of the HbD and the partial pressure of carbon dioxide (pCO2). We performed a transfer function analysis in order to calculate the gain and phase of the HbD/MABP and HbD/PCO2 subsystems. Due to the fact that cerebral autoregulation may be absent in sick premature infants, we then investigated how well these parameters could predict clinical outcome in this population. |
format |
Capítulo de libro (Book Chapter) |
author |
Caicedo Dorado, Alexander Naulaers, Gunnar Wolf, Martin Lemmers, Petra Van Bel, Frank Ameye, Lieveke Van Huffel, Sabine Van |
author_facet |
Caicedo Dorado, Alexander Naulaers, Gunnar Wolf, Martin Lemmers, Petra Van Bel, Frank Ameye, Lieveke Van Huffel, Sabine Van |
author_sort |
Caicedo Dorado, Alexander |
title |
Assessment of the Myogenic and Metabolic Mechanism Influence in Cerebral Autoregulation Using Near-Infrared Spectroscopy |
title_short |
Assessment of the Myogenic and Metabolic Mechanism Influence in Cerebral Autoregulation Using Near-Infrared Spectroscopy |
title_full |
Assessment of the Myogenic and Metabolic Mechanism Influence in Cerebral Autoregulation Using Near-Infrared Spectroscopy |
title_fullStr |
Assessment of the Myogenic and Metabolic Mechanism Influence in Cerebral Autoregulation Using Near-Infrared Spectroscopy |
title_full_unstemmed |
Assessment of the Myogenic and Metabolic Mechanism Influence in Cerebral Autoregulation Using Near-Infrared Spectroscopy |
title_sort |
assessment of the myogenic and metabolic mechanism influence in cerebral autoregulation using near-infrared spectroscopy |
publisher |
Springer Nature |
publishDate |
2011 |
url |
https://repository.urosario.edu.co/handle/10336/28880 https://doi.org/10.1007/978-1-4614-1566-4_6 |
_version_ |
1676708455045398528 |
score |
12,131701 |