Vista Equipo: A New Framework for the Assessment of Cerebral Hemodynamics Regulation in Neonates Using NIRS

A New Framework for the Assessment of Cerebral Hemodynamics Regulation in Neonates Using NIRS

We present a new framework for the assessment of cerebral hemodynamics regulation (CHR) in neonates using near-infrared spectroscopy (NIRS). In premature infants, NIRS measurements have been used as surrogate variables for cerebral blood flow (CBF) in the assessment of cerebral autoregulation (CA)....

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Detalles Bibliográficos
Autores Principales:	Caicedo Dorado, Alexander, Alderliesten, Thomas, Naulaers, Gunnar, Lemmers, Petra, Van Bel, Frank, Van Huffel, Sabine
Formato:	Capítulo de libro (Book Chapter)
Lenguaje:	Inglés (English)
Publicado:	Springer Nature 2016
Materias:	Cerebral autoregulation NIRS Multivariable Premature infants
Acceso en línea:	https://repository.urosario.edu.co/handle/10336/28876 https://doi.org/10.1007/978-1-4939-3023-4_63

id	ir-10336-28876
recordtype	dspace
spelling	ir-10336-288762020-08-28T15:50:42Z A New Framework for the Assessment of Cerebral Hemodynamics Regulation in Neonates Using NIRS Un nuevo marco para la evaluación de la regulación de la hemodinámica cerebral en recién nacidos mediante NIRS Caicedo Dorado, Alexander Alderliesten, Thomas Naulaers, Gunnar Lemmers, Petra Van Bel, Frank Van Huffel, Sabine Cerebral autoregulation NIRS Multivariable Premature infants We present a new framework for the assessment of cerebral hemodynamics regulation (CHR) in neonates using near-infrared spectroscopy (NIRS). In premature infants, NIRS measurements have been used as surrogate variables for cerebral blood flow (CBF) in the assessment of cerebral autoregulation (CA). However, NIRS measurements only reflect changes in CBF under constant changes in arterial oxygen saturation (SaO2). This condition is unlikely to be met at the bedside in the NICU. Additionally, CA is just one of the different highly coupled mechanisms that regulate brain hemodynamics. Traditional methods for the assessment of CA do not take into account the multivariate nature of CHR, producing inconclusive results. In this study we propose a newly developed multivariate methodology for the assessment of CHR. This method is able to effectively decouple the influences of SaO2 from the NIRS measurements, and at the same time, produces scores indicating the strength of the coupling between the systemic variables and NIRS recordings. We explore the use of this method, and its derived scores, for the monitoring of CHR using data from premature infants who developed a grade III-IV intra-ventricular hemorrhage during the first 3 days of life. 2016 2020-08-28T15:49:59Z info:eu-repo/semantics/bookPart info:eu-repo/semantics/publishedVersion ISBN: 978-1-4939-3022-7 https://repository.urosario.edu.co/handle/10336/28876 https://doi.org/10.1007/978-1-4939-3023-4_63 eng info:eu-repo/semantics/restrictedAccess application/pdf Springer Nature Advances in Experimental Medicine and Biology
institution	EdocUR - Universidad del Rosario
collection	DSpace
language	Inglés (English)
topic	Cerebral autoregulation NIRS Multivariable Premature infants
spellingShingle	Cerebral autoregulation NIRS Multivariable Premature infants Caicedo Dorado, Alexander Alderliesten, Thomas Naulaers, Gunnar Lemmers, Petra Van Bel, Frank Van Huffel, Sabine A New Framework for the Assessment of Cerebral Hemodynamics Regulation in Neonates Using NIRS
description	We present a new framework for the assessment of cerebral hemodynamics regulation (CHR) in neonates using near-infrared spectroscopy (NIRS). In premature infants, NIRS measurements have been used as surrogate variables for cerebral blood flow (CBF) in the assessment of cerebral autoregulation (CA). However, NIRS measurements only reflect changes in CBF under constant changes in arterial oxygen saturation (SaO2). This condition is unlikely to be met at the bedside in the NICU. Additionally, CA is just one of the different highly coupled mechanisms that regulate brain hemodynamics. Traditional methods for the assessment of CA do not take into account the multivariate nature of CHR, producing inconclusive results. In this study we propose a newly developed multivariate methodology for the assessment of CHR. This method is able to effectively decouple the influences of SaO2 from the NIRS measurements, and at the same time, produces scores indicating the strength of the coupling between the systemic variables and NIRS recordings. We explore the use of this method, and its derived scores, for the monitoring of CHR using data from premature infants who developed a grade III-IV intra-ventricular hemorrhage during the first 3 days of life.
format	Capítulo de libro (Book Chapter)
author	Caicedo Dorado, Alexander Alderliesten, Thomas Naulaers, Gunnar Lemmers, Petra Van Bel, Frank Van Huffel, Sabine
author_facet	Caicedo Dorado, Alexander Alderliesten, Thomas Naulaers, Gunnar Lemmers, Petra Van Bel, Frank Van Huffel, Sabine
author_sort	Caicedo Dorado, Alexander
title	A New Framework for the Assessment of Cerebral Hemodynamics Regulation in Neonates Using NIRS
title_short	A New Framework for the Assessment of Cerebral Hemodynamics Regulation in Neonates Using NIRS
title_full	A New Framework for the Assessment of Cerebral Hemodynamics Regulation in Neonates Using NIRS
title_fullStr	A New Framework for the Assessment of Cerebral Hemodynamics Regulation in Neonates Using NIRS
title_full_unstemmed	A New Framework for the Assessment of Cerebral Hemodynamics Regulation in Neonates Using NIRS
title_sort	new framework for the assessment of cerebral hemodynamics regulation in neonates using nirs
publisher	Springer Nature
publishDate	2016
url	https://repository.urosario.edu.co/handle/10336/28876 https://doi.org/10.1007/978-1-4939-3023-4_63
_version_	1676708405628108800
score	11,381624

A New Framework for the Assessment of Cerebral Hemodynamics Regulation in Neonates Using NIRS

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