Intrinsic properties and functional changes in spastic muscle after application of BTX-A in children with cerebral palsy: systematic review

Objective: This article aimed to review the literature to verify the effect of botulinum toxin type A (BTX-A) on the intrinsic properties of spastic muscles and functionality in children with cerebral palsy (CP). Methods: A literature search was conducted in the following databases: CINAHL, SCOPUS,...

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Autores Principales: García Salazar, Luisa Fernanda, Lopes dos Santos, Gabriela, Pavao, Silvia Letícia, Cicuto Ferreira Rocha, Nelci Adriana, de Russo, Thiago Luiz
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: Taylor & Francis 2014
Materias:
Acceso en línea:https://repository.urosario.edu.co/handle/10336/28451
https://doi.org/10.3109/17518423.2014.948640
id ir-10336-28451
recordtype dspace
spelling ir-10336-284512020-08-28T15:48:13Z Intrinsic properties and functional changes in spastic muscle after application of BTX-A in children with cerebral palsy: systematic review Propiedades intrínsecas y cambios funcionales en el músculo espástico después de la aplicación de BTX-A en niños con parálisis cerebral: revisión sistemática García Salazar, Luisa Fernanda Lopes dos Santos, Gabriela Pavao, Silvia Letícia Cicuto Ferreira Rocha, Nelci Adriana de Russo, Thiago Luiz Botulinum toxin Functionality Motor developmental Muscle spasticity Rehabilitation Objective: This article aimed to review the literature to verify the effect of botulinum toxin type A (BTX-A) on the intrinsic properties of spastic muscles and functionality in children with cerebral palsy (CP). Methods: A literature search was conducted in the following databases: CINAHL, SCOPUS, Web of Science and PubMed. Database searches were limited to the period from January 1993 to March 2014. Results: A total of 2182 papers were identified, and 17 met the inclusion criteria. Only one study analyzed the effect of the toxin on muscle intrinsic properties and others analyzed the effect on functionality. Conclusion: BTX-A application demonstrated no changes in the passive stiffness of spastic muscle. In relation to functional level, the evidence of BTX-A effect was controversial. These studies showed methodological quality limitations that restrict the interpretation of the results for the entire CP population, which justifies the need for further randomized controlled trials. 2014-09-02 2020-08-28T15:48:13Z info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion ISSN: 1751-8423 EISSN: 1751-8431 https://repository.urosario.edu.co/handle/10336/28451 https://doi.org/10.3109/17518423.2014.948640 eng info:eu-repo/semantics/restrictedAccess application/pdf Taylor & Francis Developmental Neurorehabilitation
institution EdocUR - Universidad del Rosario
collection DSpace
language Inglés (English)
topic Botulinum toxin
Functionality
Motor developmental
Muscle spasticity
Rehabilitation
spellingShingle Botulinum toxin
Functionality
Motor developmental
Muscle spasticity
Rehabilitation
García Salazar, Luisa Fernanda
Lopes dos Santos, Gabriela
Pavao, Silvia Letícia
Cicuto Ferreira Rocha, Nelci Adriana
de Russo, Thiago Luiz
Intrinsic properties and functional changes in spastic muscle after application of BTX-A in children with cerebral palsy: systematic review
description Objective: This article aimed to review the literature to verify the effect of botulinum toxin type A (BTX-A) on the intrinsic properties of spastic muscles and functionality in children with cerebral palsy (CP). Methods: A literature search was conducted in the following databases: CINAHL, SCOPUS, Web of Science and PubMed. Database searches were limited to the period from January 1993 to March 2014. Results: A total of 2182 papers were identified, and 17 met the inclusion criteria. Only one study analyzed the effect of the toxin on muscle intrinsic properties and others analyzed the effect on functionality. Conclusion: BTX-A application demonstrated no changes in the passive stiffness of spastic muscle. In relation to functional level, the evidence of BTX-A effect was controversial. These studies showed methodological quality limitations that restrict the interpretation of the results for the entire CP population, which justifies the need for further randomized controlled trials.
format Artículo (Article)
author García Salazar, Luisa Fernanda
Lopes dos Santos, Gabriela
Pavao, Silvia Letícia
Cicuto Ferreira Rocha, Nelci Adriana
de Russo, Thiago Luiz
author_facet García Salazar, Luisa Fernanda
Lopes dos Santos, Gabriela
Pavao, Silvia Letícia
Cicuto Ferreira Rocha, Nelci Adriana
de Russo, Thiago Luiz
author_sort García Salazar, Luisa Fernanda
title Intrinsic properties and functional changes in spastic muscle after application of BTX-A in children with cerebral palsy: systematic review
title_short Intrinsic properties and functional changes in spastic muscle after application of BTX-A in children with cerebral palsy: systematic review
title_full Intrinsic properties and functional changes in spastic muscle after application of BTX-A in children with cerebral palsy: systematic review
title_fullStr Intrinsic properties and functional changes in spastic muscle after application of BTX-A in children with cerebral palsy: systematic review
title_full_unstemmed Intrinsic properties and functional changes in spastic muscle after application of BTX-A in children with cerebral palsy: systematic review
title_sort intrinsic properties and functional changes in spastic muscle after application of btx-a in children with cerebral palsy: systematic review
publisher Taylor & Francis
publishDate 2014
url https://repository.urosario.edu.co/handle/10336/28451
https://doi.org/10.3109/17518423.2014.948640
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score 11,39291