Therapy for ocular toxoplasmosis
Purpose: To review current evidence for the treatment of ocular toxoplasmosis (OT). Design: Narrative review and expert recommendations. Methods: Meta-analysis and selected original articles from the medical literature were reviewed critically. Expert recommendations were analyzed. Results: Numerous...
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| Formato: | Artículo (Article) |
| Lenguaje: | Inglés (English) |
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International Uveitis Study Group
2011
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| Acceso en línea: | https://repository.urosario.edu.co/handle/10336/28441 https://doi.org/10.3109/09273948.2011.608915 |
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ir-10336-284412021-08-26T11:37:10Z Therapy for ocular toxoplasmosis Terapia para la toxoplasmosis ocular de-la-Torre, Alejandra Stanford, Miles Curi, Andre Jaffe, Glenn J. Gomez-Marin, Jorge E. Antibiotics Ocular toxoplasmosis Recurrences Steroids Therapy Treatment Uveitis Purpose: To review current evidence for the treatment of ocular toxoplasmosis (OT). Design: Narrative review and expert recommendations. Methods: Meta-analysis and selected original articles from the medical literature were reviewed critically. Expert recommendations were analyzed. Results: Numerous observational studies suggest a benefit of short-term antimicrobial therapy for toxoplasmic retinochoroiditis in immunocompetent patients, although its efficacy has not been proven in randomized clinical trials. A randomized clinical trial revealed that intermittent trimethoprim/sulfamethoxazole treatment could decrease the rate of recurrence in high-risk patients. Intravitreal injection of clindamycin and dexamethasone was an acceptable alternative to the classic treatment for OT in a randomized clinical trial. Conclusions: Opinions about therapy differ and controversy remains about its type, efficacy, and length. Intravitreal therapy may be promising for OT. A recent description of the presence of parasitemia in patients with active and inactive ocular toxoplasmosis raises new questions that need to be explored. 2011-10-04 2020-08-28T15:48:12Z info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion ISSN: 0927-3948 EISSN: 1744-5078 https://repository.urosario.edu.co/handle/10336/28441 https://doi.org/10.3109/09273948.2011.608915 eng info:eu-repo/semantics/restrictedAccess application/pdf International Uveitis Study Group Uveitis Society of India Ocular Immunology and Inflammation |
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EdocUR - Universidad del Rosario |
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DSpace |
| language |
Inglés (English) |
| topic |
Antibiotics Ocular toxoplasmosis Recurrences Steroids Therapy Treatment Uveitis |
| spellingShingle |
Antibiotics Ocular toxoplasmosis Recurrences Steroids Therapy Treatment Uveitis de-la-Torre, Alejandra Stanford, Miles Curi, Andre Jaffe, Glenn J. Gomez-Marin, Jorge E. Therapy for ocular toxoplasmosis |
| description |
Purpose: To review current evidence for the treatment of ocular toxoplasmosis (OT). Design: Narrative review and expert recommendations. Methods: Meta-analysis and selected original articles from the medical literature were reviewed critically. Expert recommendations were analyzed. Results: Numerous observational studies suggest a benefit of short-term antimicrobial therapy for toxoplasmic retinochoroiditis in immunocompetent patients, although its efficacy has not been proven in randomized clinical trials. A randomized clinical trial revealed that intermittent trimethoprim/sulfamethoxazole treatment could decrease the rate of recurrence in high-risk patients. Intravitreal injection of clindamycin and dexamethasone was an acceptable alternative to the classic treatment for OT in a randomized clinical trial. Conclusions: Opinions about therapy differ and controversy remains about its type, efficacy, and length. Intravitreal therapy may be promising for OT. A recent description of the presence of parasitemia in patients with active and inactive ocular toxoplasmosis raises new questions that need to be explored. |
| format |
Artículo (Article) |
| author |
de-la-Torre, Alejandra Stanford, Miles Curi, Andre Jaffe, Glenn J. Gomez-Marin, Jorge E. |
| author_facet |
de-la-Torre, Alejandra Stanford, Miles Curi, Andre Jaffe, Glenn J. Gomez-Marin, Jorge E. |
| author_sort |
de-la-Torre, Alejandra |
| title |
Therapy for ocular toxoplasmosis |
| title_short |
Therapy for ocular toxoplasmosis |
| title_full |
Therapy for ocular toxoplasmosis |
| title_fullStr |
Therapy for ocular toxoplasmosis |
| title_full_unstemmed |
Therapy for ocular toxoplasmosis |
| title_sort |
therapy for ocular toxoplasmosis |
| publisher |
International Uveitis Study Group |
| publishDate |
2011 |
| url |
https://repository.urosario.edu.co/handle/10336/28441 https://doi.org/10.3109/09273948.2011.608915 |
| _version_ |
1712098553290031104 |
| score |
12,131701 |