Autoimmune (auto-inflammatory) syndrome induced by adjuvants (ASIA)--animal models as a proof of concept

ASIA syndrome, “Autoimmune (Auto-inflammatory) Syndromes Induced by Adjuvants” includes at least four conditions which share a similar complex of signs and symptoms and have been defined by hyperactive immune responses: siliconosis, macrophagic myofasciitis syndrome, Gulf war syndrome and post-vacci...

Descripción completa

Detalles Bibliográficos
Autores Principales: Cruz Tapias, Paola, Agmon Levin, Nancy, Israeli, Eitan, Anaya, Juan Manuel, Shoenfeld, Yehuda
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: Bethamscience 2013
Materias:
Acceso en línea:https://repository.urosario.edu.co/handle/10336/28440
id ir-10336-28440
recordtype dspace
spelling ir-10336-284402020-08-28T15:48:12Z Autoimmune (auto-inflammatory) syndrome induced by adjuvants (ASIA)--animal models as a proof of concept Síndrome autoinmune (autoinflamatorio) inducido por adyuvantes (ASIA): modelos animales como prueba de concepto Cruz Tapias, Paola Agmon Levin, Nancy Israeli, Eitan Anaya, Juan Manuel Shoenfeld, Yehuda ASIA Autoimmune syndrome Adjuvants Animal models; Autoinflammatory syndrome ASIA syndrome, “Autoimmune (Auto-inflammatory) Syndromes Induced by Adjuvants” includes at least four conditions which share a similar complex of signs and symptoms and have been defined by hyperactive immune responses: siliconosis, macrophagic myofasciitis syndrome, Gulf war syndrome and post-vaccination phenomena. Exposure to adjuvants has been documented in these four medical conditions, suggesting that the common denominator to these syndromes is a trigger entailing adjuvant activity. An important role of animal models in proving the ASIA concept has been established. Experimentally animal models of autoimmune diseases induced by adjuvants are currently widely used to understand the mechanisms and etiology and pathogenesis of these diseases and might thus promote the development of new diagnostic, predictive and therapeutic methods. In the current review we wish to unveil the variety of ASIA animal models associated with systemic and organ specific autoimmune diseases induced by adjuvants. We included in this review animal models for rheumatoid arthritis-like disease, for systemic lupus erythematosus-like disease, autoimmune thyroid disease-like disease, antiphospholipid syndrome, myocarditis and others. All these models support the concept of ASIA, as the Autoimmune (Auto-inflammatory) Syndrome Induced by Adjuvants. 2013-10-01 2020-08-28T15:48:12Z info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion ISSN : 0929-8673 https://repository.urosario.edu.co/handle/10336/28440 eng info:eu-repo/semantics/closedAccess application/pdf Bethamscience Current Medicinal Chemistry
institution EdocUR - Universidad del Rosario
collection DSpace
language Inglés (English)
topic ASIA
Autoimmune syndrome
Adjuvants
Animal models;
Autoinflammatory syndrome
spellingShingle ASIA
Autoimmune syndrome
Adjuvants
Animal models;
Autoinflammatory syndrome
Cruz Tapias, Paola
Agmon Levin, Nancy
Israeli, Eitan
Anaya, Juan Manuel
Shoenfeld, Yehuda
Autoimmune (auto-inflammatory) syndrome induced by adjuvants (ASIA)--animal models as a proof of concept
description ASIA syndrome, “Autoimmune (Auto-inflammatory) Syndromes Induced by Adjuvants” includes at least four conditions which share a similar complex of signs and symptoms and have been defined by hyperactive immune responses: siliconosis, macrophagic myofasciitis syndrome, Gulf war syndrome and post-vaccination phenomena. Exposure to adjuvants has been documented in these four medical conditions, suggesting that the common denominator to these syndromes is a trigger entailing adjuvant activity. An important role of animal models in proving the ASIA concept has been established. Experimentally animal models of autoimmune diseases induced by adjuvants are currently widely used to understand the mechanisms and etiology and pathogenesis of these diseases and might thus promote the development of new diagnostic, predictive and therapeutic methods. In the current review we wish to unveil the variety of ASIA animal models associated with systemic and organ specific autoimmune diseases induced by adjuvants. We included in this review animal models for rheumatoid arthritis-like disease, for systemic lupus erythematosus-like disease, autoimmune thyroid disease-like disease, antiphospholipid syndrome, myocarditis and others. All these models support the concept of ASIA, as the Autoimmune (Auto-inflammatory) Syndrome Induced by Adjuvants.
format Artículo (Article)
author Cruz Tapias, Paola
Agmon Levin, Nancy
Israeli, Eitan
Anaya, Juan Manuel
Shoenfeld, Yehuda
author_facet Cruz Tapias, Paola
Agmon Levin, Nancy
Israeli, Eitan
Anaya, Juan Manuel
Shoenfeld, Yehuda
author_sort Cruz Tapias, Paola
title Autoimmune (auto-inflammatory) syndrome induced by adjuvants (ASIA)--animal models as a proof of concept
title_short Autoimmune (auto-inflammatory) syndrome induced by adjuvants (ASIA)--animal models as a proof of concept
title_full Autoimmune (auto-inflammatory) syndrome induced by adjuvants (ASIA)--animal models as a proof of concept
title_fullStr Autoimmune (auto-inflammatory) syndrome induced by adjuvants (ASIA)--animal models as a proof of concept
title_full_unstemmed Autoimmune (auto-inflammatory) syndrome induced by adjuvants (ASIA)--animal models as a proof of concept
title_sort autoimmune (auto-inflammatory) syndrome induced by adjuvants (asia)--animal models as a proof of concept
publisher Bethamscience
publishDate 2013
url https://repository.urosario.edu.co/handle/10336/28440
_version_ 1676708365660585984
score 11,398419