A TGF-? mediated regulatory mechanism modulates the T cell immune response to rotavirus in adults but not in children

Children with acute RV-gastroenteritis (GE) had low or undetectable levels of circulating IFN-?+, IL-13+, IL-2+, IL-10+ or IL-17+ RV-T cells. IFN-?+ T cells and low frequencies of IL-10+ and IL-2+ CD4+ T cells were found in adults with RV-GE during acute and convalescence phases, respectively. Circu...

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Detalles Bibliográficos
Autores Principales: Mesa, Martha C., Gutiérrez, Lina, Duarte-Rey, Carolina, Angel, Juana, Franco, Manuel A.
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: Elsevier 2010
Materias:
Acceso en línea:https://repository.urosario.edu.co/handle/10336/27853
https://doi.org/10.1016/j.virol.2009.12.016