Hybrid sterility, Haldane's rule and speciation in Heliconius cydno and H. melpomene

Most genetic studies of Haldane’s rule, in which hybrid sterility or inviability affects the heterogametic sex preferentially, have focused on Drosophila. It therefore remains unclear to what extent the conclusions of that work apply more generally, particularly in female-heterogametic taxa such as...

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Autores Principales: Naisbit, Russell E., Jiggins, Chris D., Linares, Mauricio, Salazar, Camilo, Mallet, James
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: Genetics Society of America 2002
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Acceso en línea:https://repository.urosario.edu.co/handle/10336/27822
id ir-10336-27822
recordtype dspace
spelling ir-10336-278222020-08-19T14:47:18Z Hybrid sterility, Haldane's rule and speciation in Heliconius cydno and H. melpomene Esterilidad híbrida, regla de Haldane y especiación en Heliconius cydno y H. melpomene Naisbit, Russell E. Jiggins, Chris D. Linares, Mauricio Salazar, Camilo Mallet, James Hybrid Sterility Haldane’s Rule Speciation Heliconius cydno H. melpomene Most genetic studies of Haldane’s rule, in which hybrid sterility or inviability affects the heterogametic sex preferentially, have focused on Drosophila. It therefore remains unclear to what extent the conclusions of that work apply more generally, particularly in female-heterogametic taxa such as birds and Lepidoptera. Here we present a genetic analysis of Haldane’s rule in Heliconius butterflies. Female F1 hybrids between Heliconius melpomene and H. cydno are completely sterile, while males have normal to mildly reduced fertility. In backcrosses of male F1 hybrids, female offspring range from completely sterile to fully fertile. Linkage analysis using the Z-linked triose-phosphate isomerase locus demonstrates a “large X” (Z) effect on sterility. Expression of female sterility varies among crosses in this and a previous study of Heliconius. Sterility may result from the production of normal but infertile eggs, production of small infertile eggs, or from a complete failure to develop ovarioles, which suggests multiple routes to the evolution of hybrid sterility in these Heliconius species. These results conform to the expectations of the “dominance” rather than “faster male” theories of Haldane’s rule and suggest that relatively few loci are responsible. The two species are broadly sympatric and hybridize in the wild, so that female hybrid sterility forms one of several strong but incomplete barriers to gene flow in nature. The effect of female sterility is comparable to that of selection against non-mimetic hybrids, while mate choice forms a much stronger barrier to gene transfer. 2002-08-01 2020-08-19T14:44:04Z info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion ISSN: 0016-6731 EISSN: 1943-2631 https://repository.urosario.edu.co/handle/10336/27822 eng info:eu-repo/semantics/openAccess application/pdf Genetics Society of America Genetics
institution EdocUR - Universidad del Rosario
collection DSpace
language Inglés (English)
topic Hybrid Sterility
Haldane’s Rule
Speciation
Heliconius cydno
H. melpomene
spellingShingle Hybrid Sterility
Haldane’s Rule
Speciation
Heliconius cydno
H. melpomene
Naisbit, Russell E.
Jiggins, Chris D.
Linares, Mauricio
Salazar, Camilo
Mallet, James
Hybrid sterility, Haldane's rule and speciation in Heliconius cydno and H. melpomene
description Most genetic studies of Haldane’s rule, in which hybrid sterility or inviability affects the heterogametic sex preferentially, have focused on Drosophila. It therefore remains unclear to what extent the conclusions of that work apply more generally, particularly in female-heterogametic taxa such as birds and Lepidoptera. Here we present a genetic analysis of Haldane’s rule in Heliconius butterflies. Female F1 hybrids between Heliconius melpomene and H. cydno are completely sterile, while males have normal to mildly reduced fertility. In backcrosses of male F1 hybrids, female offspring range from completely sterile to fully fertile. Linkage analysis using the Z-linked triose-phosphate isomerase locus demonstrates a “large X” (Z) effect on sterility. Expression of female sterility varies among crosses in this and a previous study of Heliconius. Sterility may result from the production of normal but infertile eggs, production of small infertile eggs, or from a complete failure to develop ovarioles, which suggests multiple routes to the evolution of hybrid sterility in these Heliconius species. These results conform to the expectations of the “dominance” rather than “faster male” theories of Haldane’s rule and suggest that relatively few loci are responsible. The two species are broadly sympatric and hybridize in the wild, so that female hybrid sterility forms one of several strong but incomplete barriers to gene flow in nature. The effect of female sterility is comparable to that of selection against non-mimetic hybrids, while mate choice forms a much stronger barrier to gene transfer.
format Artículo (Article)
author Naisbit, Russell E.
Jiggins, Chris D.
Linares, Mauricio
Salazar, Camilo
Mallet, James
author_facet Naisbit, Russell E.
Jiggins, Chris D.
Linares, Mauricio
Salazar, Camilo
Mallet, James
author_sort Naisbit, Russell E.
title Hybrid sterility, Haldane's rule and speciation in Heliconius cydno and H. melpomene
title_short Hybrid sterility, Haldane's rule and speciation in Heliconius cydno and H. melpomene
title_full Hybrid sterility, Haldane's rule and speciation in Heliconius cydno and H. melpomene
title_fullStr Hybrid sterility, Haldane's rule and speciation in Heliconius cydno and H. melpomene
title_full_unstemmed Hybrid sterility, Haldane's rule and speciation in Heliconius cydno and H. melpomene
title_sort hybrid sterility, haldane's rule and speciation in heliconius cydno and h. melpomene
publisher Genetics Society of America
publishDate 2002
url https://repository.urosario.edu.co/handle/10336/27822
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score 11,383811