Human polymorphism at microRNAs and microRNA target sites
MicroRNAs (miRNAs) function as endogenous translational repressors of protein-coding genes in animals by binding to target sites in the 3? UTRs of mRNAs. Because a single nucleotide change in the sequence of a target site can affect miRNA regulation, naturally occurring SNPs in target sites are cand...
Autores Principales: | , , |
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Formato: | Artículo (Article) |
Lenguaje: | Inglés (English) |
Publicado: |
National Academy of Sciences
2007
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Materias: | |
Acceso en línea: | https://repository.urosario.edu.co/handle/10336/27817 https://doi.org/10.1073/pnas.0611347104 |