Vista Equipo: Exercise dose-response of the V? E/V?CO 2 slope in postmenopausal women in the DREW study

Exercise dose-response of the V? E/V?CO 2 slope in postmenopausal women in the DREW study

"Purpose: Being overweight/obese, having hypertension, and being postmenopausal are risk factors for the development of congestive heart failure (CHF). A characteristic of CHF is an abnormal V?E/V?CO2 slope, which is predictive of mortality in patients with CHF. Although the V?E/V?CO2 slope is...

Descripción completa

Detalles Bibliográficos
Autores Principales:	Anaya, Stephanie A., Church, Timothy S., Blair, Steven N., Myers, Jonathan N., Earnest, Conrad P.
Formato:	Artículo (Article)
Lenguaje:	Inglés (English)
Publicado:	American College of Sports Medicine 2009
Materias:	Blood pressure Sedentary Ventilatory efficiency Cardiorespiratory fitness
Acceso en línea:	https://repository.urosario.edu.co/handle/10336/27702 https://doi.org/10.1249/MSS.0b013e3181930009

id	ir-10336-27702
recordtype	dspace
spelling	ir-10336-277022020-08-19T14:43:25Z Exercise dose-response of the V? E/V?CO 2 slope in postmenopausal women in the DREW study Ejercicio dosis-respuesta de la pendiente V? E / V?CO 2 en mujeres posmenopáusicas en el estudio DREW Anaya, Stephanie A. Church, Timothy S. Blair, Steven N. Myers, Jonathan N. Earnest, Conrad P. Blood pressure Sedentary Ventilatory efficiency Cardiorespiratory fitness "Purpose: Being overweight/obese, having hypertension, and being postmenopausal are risk factors for the development of congestive heart failure (CHF). A characteristic of CHF is an abnormal V?E/V?CO2 slope, which is predictive of mortality in patients with CHF. Although the V?E/V?CO2 slope is well established in CHF patients, little is known regarding interventions for ""at-risk"" populations. Methods: We examined the V?E/V?CO2 slope in 401 sedentary, overweight, moderately hypertensive women randomized to 6 m of nonexercise (control) or 4 kcal·kg?1·wk?1 (KKW), 8 KKW, or 12 KKW of exercise at an intensity corresponding to 50% of baseline V?O2max. We examined trends in exercise treatment dose versus change in mean V?E/V?CO2 slope using a linear regression model (KKW vs V?E/V?CO2 slope) and a linear mixed model. Results: Regression analysis showed a significant trend for a reduction in the V?E/V?CO2 slope from baseline (mean ± SD: 32.6 ± 6.3; P < 0.004). When expressed as mean change (95% confidence interval (CI)) from baseline, we observed significant reductions in the V?E/V?CO2 slope for the 8-KKW (?1.14; 95% CI, ?1.5 to ?0.2) and 12-KKW (?1.67; 95% CI, ?2.3 to ?0.3) groups. No significant effect was noted for the 4-KKW (?0.4; 95% CI, ?1.2 to 0.15) group. Conclusion: Moderate-intensity aerobic exercise at doses of 8 KKW or greater seems to present an adequate dose of exercise to promote small but significant reductions in the V?E/V?CO2 slope in postmenopausal women who exhibit risk factors associated with the development of CHF." 2009-05 2020-08-19T14:43:25Z info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion ISSN: 0195-9131 EISSN: 1530-0315 https://repository.urosario.edu.co/handle/10336/27702 https://doi.org/10.1249/MSS.0b013e3181930009 eng info:eu-repo/semantics/openAccess application/pdf American College of Sports Medicine Medicine and Science in Sports and Exercise
institution	EdocUR - Universidad del Rosario
collection	DSpace
language	Inglés (English)
topic	Blood pressure Sedentary Ventilatory efficiency Cardiorespiratory fitness
spellingShingle	Blood pressure Sedentary Ventilatory efficiency Cardiorespiratory fitness Anaya, Stephanie A. Church, Timothy S. Blair, Steven N. Myers, Jonathan N. Earnest, Conrad P. Exercise dose-response of the V? E/V?CO 2 slope in postmenopausal women in the DREW study
description	"Purpose: Being overweight/obese, having hypertension, and being postmenopausal are risk factors for the development of congestive heart failure (CHF). A characteristic of CHF is an abnormal V?E/V?CO2 slope, which is predictive of mortality in patients with CHF. Although the V?E/V?CO2 slope is well established in CHF patients, little is known regarding interventions for ""at-risk"" populations. Methods: We examined the V?E/V?CO2 slope in 401 sedentary, overweight, moderately hypertensive women randomized to 6 m of nonexercise (control) or 4 kcal·kg?1·wk?1 (KKW), 8 KKW, or 12 KKW of exercise at an intensity corresponding to 50% of baseline V?O2max. We examined trends in exercise treatment dose versus change in mean V?E/V?CO2 slope using a linear regression model (KKW vs V?E/V?CO2 slope) and a linear mixed model. Results: Regression analysis showed a significant trend for a reduction in the V?E/V?CO2 slope from baseline (mean ± SD: 32.6 ± 6.3; P < 0.004). When expressed as mean change (95% confidence interval (CI)) from baseline, we observed significant reductions in the V?E/V?CO2 slope for the 8-KKW (?1.14; 95% CI, ?1.5 to ?0.2) and 12-KKW (?1.67; 95% CI, ?2.3 to ?0.3) groups. No significant effect was noted for the 4-KKW (?0.4; 95% CI, ?1.2 to 0.15) group. Conclusion: Moderate-intensity aerobic exercise at doses of 8 KKW or greater seems to present an adequate dose of exercise to promote small but significant reductions in the V?E/V?CO2 slope in postmenopausal women who exhibit risk factors associated with the development of CHF."
format	Artículo (Article)
author	Anaya, Stephanie A. Church, Timothy S. Blair, Steven N. Myers, Jonathan N. Earnest, Conrad P.
author_facet	Anaya, Stephanie A. Church, Timothy S. Blair, Steven N. Myers, Jonathan N. Earnest, Conrad P.
author_sort	Anaya, Stephanie A.
title	Exercise dose-response of the V? E/V?CO 2 slope in postmenopausal women in the DREW study
title_short	Exercise dose-response of the V? E/V?CO 2 slope in postmenopausal women in the DREW study
title_full	Exercise dose-response of the V? E/V?CO 2 slope in postmenopausal women in the DREW study
title_fullStr	Exercise dose-response of the V? E/V?CO 2 slope in postmenopausal women in the DREW study
title_full_unstemmed	Exercise dose-response of the V? E/V?CO 2 slope in postmenopausal women in the DREW study
title_sort	exercise dose-response of the v? e/v?co 2 slope in postmenopausal women in the drew study
publisher	American College of Sports Medicine
publishDate	2009
url	https://repository.urosario.edu.co/handle/10336/27702 https://doi.org/10.1249/MSS.0b013e3181930009
_version_	1676074322023677952
score	11,383075

Exercise dose-response of the V? E/V?CO 2 slope in postmenopausal women in the DREW study

Ejemplares similares