A Mutation in DAOA Modifies the Age of Onset in PSEN1 E280A Alzheimer's Disease
We previously reported age of onset (AOO) modifier genes in the world’s largest pedigree segregating early-onset Alzheimer’s disease (AD), caused by the p.Glu280Ala (E280A) mutation in the PSEN1 gene. Here we report the results of a targeted analysis of functional exonic variants in those AOO modifi...
Autores Principales: | , , , , , , , , , |
---|---|
Formato: | Artículo (Article) |
Lenguaje: | Inglés (English) |
Publicado: |
Hindawi
2016
|
Materias: | |
Acceso en línea: | https://repository.urosario.edu.co/handle/10336/27575 https://doi.org/10.1155/2016/9760314 |