Chronic intrathecal baclofen administration in severe spasticity

On the basis of previous experimental and clinical studies, 14 patients with severe spasticity due to central or spinal cord damage, resistant to all conservative treatments, were selected after a percutaneous trial period for chronic intrathecal baclofen infusion by programmable pumps. The agent wa...

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Autores Principales: Broseta, J., Garcia-March, G., Sánchez-Ledesma, M.J., Anaya, Juan-Manuel, Silva, I.
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: Karger AG 1990
Materias:
Acceso en línea:https://repository.urosario.edu.co/handle/10336/27366
https://doi.org/10.1159/000100205
id ir-10336-27366
recordtype dspace
spelling ir-10336-273662021-08-05T22:27:53Z Chronic intrathecal baclofen administration in severe spasticity Administración crónica de baclofeno intratecal en espasticidad severa Broseta, J. Garcia-March, G. Sánchez-Ledesma, M.J. Anaya, Juan-Manuel Silva, I. Baclofen Spasticity Programmable pumps Spinal infusion On the basis of previous experimental and clinical studies, 14 patients with severe spasticity due to central or spinal cord damage, resistant to all conservative treatments, were selected after a percutaneous trial period for chronic intrathecal baclofen infusion by programmable pumps. The agent was delivered at C4 in quadriplegic patients or in cases with central spasticity and in the neighbouring areas on the affected segments in paraplegic patients. The daily baclofen dose varied from 25 to 260 µg and was infused in a bolus, continuously infused or both combined according to the results during the trial period. After a mean follow-up period of 11 months, constant decrease of rigidity, absence of spasms, improvement of bladder function, cramping pain remission, and moderate improvement in walking capacity and transfer activities were usually observed. Neither complications nor side effects were noted. 1990-11-28 2020-08-19T14:41:54Z info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion ISSN: 1011-6125 EISSN: 1423-0372 https://repository.urosario.edu.co/handle/10336/27366 https://doi.org/10.1159/000100205 eng info:eu-repo/semantics/restrictedAccess application/pdf Karger AG Stereotactic and Functional Neurosurgery
institution EdocUR - Universidad del Rosario
collection DSpace
language Inglés (English)
topic Baclofen
Spasticity
Programmable pumps
Spinal infusion
spellingShingle Baclofen
Spasticity
Programmable pumps
Spinal infusion
Broseta, J.
Garcia-March, G.
Sánchez-Ledesma, M.J.
Anaya, Juan-Manuel
Silva, I.
Chronic intrathecal baclofen administration in severe spasticity
description On the basis of previous experimental and clinical studies, 14 patients with severe spasticity due to central or spinal cord damage, resistant to all conservative treatments, were selected after a percutaneous trial period for chronic intrathecal baclofen infusion by programmable pumps. The agent was delivered at C4 in quadriplegic patients or in cases with central spasticity and in the neighbouring areas on the affected segments in paraplegic patients. The daily baclofen dose varied from 25 to 260 µg and was infused in a bolus, continuously infused or both combined according to the results during the trial period. After a mean follow-up period of 11 months, constant decrease of rigidity, absence of spasms, improvement of bladder function, cramping pain remission, and moderate improvement in walking capacity and transfer activities were usually observed. Neither complications nor side effects were noted.
format Artículo (Article)
author Broseta, J.
Garcia-March, G.
Sánchez-Ledesma, M.J.
Anaya, Juan-Manuel
Silva, I.
author_facet Broseta, J.
Garcia-March, G.
Sánchez-Ledesma, M.J.
Anaya, Juan-Manuel
Silva, I.
author_sort Broseta, J.
title Chronic intrathecal baclofen administration in severe spasticity
title_short Chronic intrathecal baclofen administration in severe spasticity
title_full Chronic intrathecal baclofen administration in severe spasticity
title_fullStr Chronic intrathecal baclofen administration in severe spasticity
title_full_unstemmed Chronic intrathecal baclofen administration in severe spasticity
title_sort chronic intrathecal baclofen administration in severe spasticity
publisher Karger AG
publishDate 1990
url https://repository.urosario.edu.co/handle/10336/27366
https://doi.org/10.1159/000100205
_version_ 1712098552187977728
score 12,131701