5azadC treatment upregulates miR-375 level and represses HPV16 E6 expression

High-risk human papillomaviruses are the etiological agents of cervical cancer and HPV16 is the most oncogenic genotype. Immortalization and transformation of infected cells requires the overexpression of the two viral oncoproteins E6 and E7 following HPV DNA integration into the host cell genome. I...

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Detalles Bibliográficos
Autores Principales: Morel, Adrien, Baguet, Aurélie, Perrard, Jérôme, Demeret, Caroline, Jacquin, Elise, Guenat, David, Mougin, Christiane, Prétet, Jean-Luc
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: Impact Journals 2017
Materias:
HPV
E6
Acceso en línea:https://repository.urosario.edu.co/handle/10336/27298
https://doi.org/10.18632/oncotarget.17575