Rheumatoid arthritis association in Colombian population is restricted to HLA-DRB1*04 QRRAA alleles

In most ethnic groups genetic susceptibility to rheumatoid arthritis (RA) is associated with certain HLA-DRB1 alleles encoding a similar sequence motif called the 'shared epitope' (SE) spanning amino acid positions 70 to 74 in the third diversity region of the outermost domain of the HLA-D...

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Detalles Bibliográficos
Autores Principales: Anaya, Juan-Manuel, Correa, PA, Mantilla, RD, Arcos-Burgos, M
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: Nature Publishing Group 2002
Materias:
Acceso en línea:https://repository.urosario.edu.co/handle/10336/26904
https://doi.org/10.1038/sj.gene.6363833