%0 Otro (Other) %A Anaya, Juan-Manuel %I Elsevier %D 2017 %G Inglés (English) %T The autoimmune tautology. A summary of evidence %U https://repository.urosario.edu.co/handle/10336/26355 %U https://doi.org/10.1016/j.jbspin.2016.11.012 %X Autoimmune diseases (ADs) represent a heterogeneous group of chronic conditions that affect specific target organs or multiple organ systems, and are initiated by the loss of immunological tolerance to self-antigens. The chronic nature of these diseases places a significant burden on the utilization of medical care, direct and indirect economic costs, and quality of life.