Frontline Science: Targeted expression of a dominant-negative high mobility group A1 transgene improves outcome in sepsis
High mobility group (HMG) proteins are a family of architectural transcription factors, with HMGA1 playing a role in the regulation of genes involved in promoting systemic inflammatory responses. We speculated that blocking HMGA1?mediated pathways might improve outcomes from sepsis. To investigate H...
Autores Principales: | , , , , , , , , , , , , , , |
---|---|
Formato: | Artículo (Article) |
Lenguaje: | Inglés (English) |
Publicado: |
John Wiley and Sons
2018
|
Materias: | |
Acceso en línea: | https://repository.urosario.edu.co/handle/10336/26325 https://doi.org/10.1002/JLB.4HI0817-333RR |