Mutations modifying sporadic Alzheimer's disease age of onset

The identification of mutations modifying the age of onset (AOO) in Alzheimer's disease (AD) is crucial for understanding the natural history of AD and, therefore, for early interventions. Patients with sporadic AD (sAD) from a genetic isolate in the extremes of the AOO distribution were whole-...

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Detalles Bibliográficos
Autores Principales: Vélez, Jorge I., Lopera, Francisco, Patel, Hardip R., Johar, Angad S., Cai, Yeping, Rivera, Dora, Tobón, Carlos, Villegas ,Andrés, Sepulveda-Falla, Diego, Lehmann, Shaun G., Easteal, Simon, Mastronardi, Claudio A., Arcos-Burgos, Mauricio
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: John Wiley and Sons 2016
Materias:
Acceso en línea:https://repository.urosario.edu.co/handle/10336/26192
https://doi.org/10.1002/ajmg.b.32493