Mutations modifying sporadic Alzheimer's disease age of onset
The identification of mutations modifying the age of onset (AOO) in Alzheimer's disease (AD) is crucial for understanding the natural history of AD and, therefore, for early interventions. Patients with sporadic AD (sAD) from a genetic isolate in the extremes of the AOO distribution were whole-...
Autores Principales: | , , , , , , , , , , , , |
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Formato: | Artículo (Article) |
Lenguaje: | Inglés (English) |
Publicado: |
John Wiley and Sons
2016
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Materias: | |
Acceso en línea: | https://repository.urosario.edu.co/handle/10336/26192 https://doi.org/10.1002/ajmg.b.32493 |