An Ultraconserved brain-specific enhancer within ADGRL3 (LPHN3) underpins attention-deficit/hyperactivity disorder susceptibility

BACKGROUND—Genetic factors predispose to attention deficit/hyperactivity disorder (ADHD). Previous studies have reported linkage and association to ADHD of gene variants within ADGRL3. In this study, we functionally analyzed non-coding variants in this gene as likely pathological contributors. METHO...

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Detalles Bibliográficos
Autores Principales: Martinez, Ariel F., Abe, Yu, Hong, Sungkook, Molyneux, Kevin, Yarnell, David, Löhr, Heiko, Driever, Wolfgang, Acosta, Maria T., Arcos-Burgos, Mauricio, Muenke, Maximilian
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: Society of Biological Psychiatry 2016
Materias:
Acceso en línea:https://repository.urosario.edu.co/handle/10336/26069
https://doi.org/10.1016/j.biopsych.2016.06.026