ETP-46321, a dual p110?/? class IA phosphoinositide 3-kinase inhibitor modulates T lymphocyte activation and collagen-induced arthritis

Class IA phosphoinositide 3-kinases (PI3Ks) are essential to function of normal and tumor cells, and to modulate immune responses. T lymphocytes express high levels of p110? and p110? class IA PI3K. Whereas the functioning of PI3K p110? in immune and autoimmune reactions is well established, the rol...

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Detalles Bibliográficos
Autores Principales: Aragoneses-Fenoll, L., Montes-Casado, M., Ojeda, G., Acosta-Ampudia, Yeny, Herranz, J., Martínez, S., Blanco-Aparicio, C., Criado, G., Pastor, J., Dianzani, U., Portolés, P., Rojo, J.M.
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://repository.urosario.edu.co/handle/10336/26038
https://doi.org/10.1016/j.bcp.2016.02.005