ETP-46321, a dual p110?/? class IA phosphoinositide 3-kinase inhibitor modulates T lymphocyte activation and collagen-induced arthritis
Class IA phosphoinositide 3-kinases (PI3Ks) are essential to function of normal and tumor cells, and to modulate immune responses. T lymphocytes express high levels of p110? and p110? class IA PI3K. Whereas the functioning of PI3K p110? in immune and autoimmune reactions is well established, the rol...
Autores Principales: | , , , , , , , , , , , |
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Formato: | Artículo (Article) |
Lenguaje: | Inglés (English) |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://repository.urosario.edu.co/handle/10336/26038 https://doi.org/10.1016/j.bcp.2016.02.005 |