Changing ABRA protein peptide to fit into the HLA-DRbeta1*0301 molecule renders it protection-inducing

The Plasmodium falciparum acidic–basic repeat antigen represents a potential malarial vaccine candidate. One of this protein’s high activity binding peptides, named 2150 (161KMNMLKENVDYIQKNQNLFK180), is conserved, non-immunogenic, and non-protection-inducing. Analogue peptides whose critical binding...

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Detalles Bibliográficos
Autores Principales: Salazar, Luz M., Alba, Martha P., Curtidor, Hernando, Bermúdez, Adriana, Vargas, Luis E., Rivera, Zuly J., Patarroyo, Manuel E.
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: Elsevier 2004
Materias:
NMR
Acceso en línea:https://repository.urosario.edu.co/handle/10336/26036
https://doi.org/10.1016/j.bbrc.2004.07.086