T-Cell-specific loss of the PI-3-linase p110? catalytic subunit results in enhanced cytokine production and antitumor response
Class IA phosphatidylinositol 3-kinase (PI3K) catalytic subunits p110? and p110? are targets in cancer therapy expressed at high levels in T lymphocytes. The role of p110? PI3K in normal or pathological immune responses is well established, yet the importance of p110? subunits in T cell-dependent im...
| Autores Principales: | , , , , , , |
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| Formato: | Artículo (Article) |
| Lenguaje: | Inglés (English) |
| Publicado: |
Frontiers Social Media
2018
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| Materias: | |
| Acceso en línea: | https://repository.urosario.edu.co/handle/10336/25984 https://doi.org/10.3389/fimmu.2018.00332 |