Chronic diarrhea as a manifestation of a neuroendocrine tumor

Neuroendocrine tumors (NETs) are a heterogeneous group of rare neoplasms that originate in endocrine cells with the ability to secrete amines and hormonal polypeptides. Pancreatic neuroendocrine tumors (PNETs) can be functional or non-functional. Functional PNETs secrete common hormones such as gast...

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Autores Principales: Sandoval A, Héctor Fabio, González C., Angélica María, Angarita C., María Camila, Rosado R., Micela Beatriz, Arenas D., Rubén Darío
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: Asociacion Colombiana de Gastroenterologia 2020
Materias:
Acceso en línea:https://repository.urosario.edu.co/handle/10336/25144
id ir-10336-25144
recordtype dspace
spelling ir-10336-251442020-08-04T19:25:53Z Chronic diarrhea as a manifestation of a neuroendocrine tumor Diarrea crónica como manifestación de un tumor neuroendocrino Sandoval A, Héctor Fabio González C., Angélica María Angarita C., María Camila Rosado R., Micela Beatriz Arenas D., Rubén Darío Chronic diarrhea Neuroendocrine tumor Secretory diarrhea Vipoma Neuroendocrine tumors (NETs) are a heterogeneous group of rare neoplasms that originate in endocrine cells with the ability to secrete amines and hormonal polypeptides. Pancreatic neuroendocrine tumors (PNETs) can be functional or non-functional. Functional PNETs secrete common hormones such as gastrin, insulin and glucagon and much less frequent hormones such as vasoactive intestinal peptide (VIP). Their characteristics depend on the peptide secreted. Vipomas are characterized by chronic diarrhea of ?secretory characteristics that usually lead to hydroelectrolytic disorders and can lead to serious complications associated with renal failure. This article describes the case of a 37-year-old man who had suffered chronic diarrhea with frequent hospitalization for hydroelectrolytic disorders for six months due to severe hypokalemia and acute renal damage due to dehydration. After multiple studies, a diagnosis of secretory diarrhea due to a VIP secretory functional NET was considered. Empirical therapy with Octreotide was begun to control diarrhea and correct the hydroelectrolytic disorder. More studies of PNETS are being published. They have been treated surgically intervention with favorable clinical results and complete remission of symptoms. © 2020 Asociaciones Colombianas de Gastroenterología, Endoscopia digestiva, Coloproctología y Hepatología. 2020 2020-06-11T13:22:30Z info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion 0120-9957 https://repository.urosario.edu.co/handle/10336/25144 eng info:eu-repo/semantics/openAccess application/pdf Asociacion Colombiana de Gastroenterologia instname:Universidad del Rosario reponame:Repositorio Institucional EdocUR
institution EdocUR - Universidad del Rosario
collection DSpace
language Inglés (English)
topic Chronic diarrhea
Neuroendocrine tumor
Secretory diarrhea
Vipoma
spellingShingle Chronic diarrhea
Neuroendocrine tumor
Secretory diarrhea
Vipoma
Sandoval A, Héctor Fabio
González C., Angélica María
Angarita C., María Camila
Rosado R., Micela Beatriz
Arenas D., Rubén Darío
Chronic diarrhea as a manifestation of a neuroendocrine tumor
description Neuroendocrine tumors (NETs) are a heterogeneous group of rare neoplasms that originate in endocrine cells with the ability to secrete amines and hormonal polypeptides. Pancreatic neuroendocrine tumors (PNETs) can be functional or non-functional. Functional PNETs secrete common hormones such as gastrin, insulin and glucagon and much less frequent hormones such as vasoactive intestinal peptide (VIP). Their characteristics depend on the peptide secreted. Vipomas are characterized by chronic diarrhea of ?secretory characteristics that usually lead to hydroelectrolytic disorders and can lead to serious complications associated with renal failure. This article describes the case of a 37-year-old man who had suffered chronic diarrhea with frequent hospitalization for hydroelectrolytic disorders for six months due to severe hypokalemia and acute renal damage due to dehydration. After multiple studies, a diagnosis of secretory diarrhea due to a VIP secretory functional NET was considered. Empirical therapy with Octreotide was begun to control diarrhea and correct the hydroelectrolytic disorder. More studies of PNETS are being published. They have been treated surgically intervention with favorable clinical results and complete remission of symptoms. © 2020 Asociaciones Colombianas de Gastroenterología, Endoscopia digestiva, Coloproctología y Hepatología.
format Artículo (Article)
author Sandoval A, Héctor Fabio
González C., Angélica María
Angarita C., María Camila
Rosado R., Micela Beatriz
Arenas D., Rubén Darío
author_facet Sandoval A, Héctor Fabio
González C., Angélica María
Angarita C., María Camila
Rosado R., Micela Beatriz
Arenas D., Rubén Darío
author_sort Sandoval A, Héctor Fabio
title Chronic diarrhea as a manifestation of a neuroendocrine tumor
title_short Chronic diarrhea as a manifestation of a neuroendocrine tumor
title_full Chronic diarrhea as a manifestation of a neuroendocrine tumor
title_fullStr Chronic diarrhea as a manifestation of a neuroendocrine tumor
title_full_unstemmed Chronic diarrhea as a manifestation of a neuroendocrine tumor
title_sort chronic diarrhea as a manifestation of a neuroendocrine tumor
publisher Asociacion Colombiana de Gastroenterologia
publishDate 2020
url https://repository.urosario.edu.co/handle/10336/25144
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score 11,828437