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Adenocarcinoma in situ and associated human papillomavirus type distribution observed in two clinical trials of a quadrivalent human papillomavirus vaccine

The primary objective of this report is to describe the detection of adenocarcinoma in situ (AIS) and associated human papillomavirus (HPV) type distribution that was observed in the context of two phase 3 clinical trials of a quadrivalent HPV6/11/16/18 vaccine. In this intention-to-treat analysis,...

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Detalles Bibliográficos
Autores Principales:	Ault K.A., Joura E.A., Kjaer S.K., Iversen O.-E., Wheeler C.M., Perez G., Brown D.R., Koutsky L.A., Garland S.M., Olsson S.-E., Tang G.W.K., Ferris D.G., Paavonen J., Steben M., Bosch F.X., Majewski S., Muñoz N., Sings H.L., Harkins K., Rutkowski M.A., Haupt R.M., Garner E.I.O.
Formato:	Artículo (Article)
Lenguaje:	Inglés (English)
Publicado:	2011
Materias:	Placebo Wart virus vaccine Adenocarcinoma in situ Adolescent Adult Article Carcinoma in situ Colposcopy Cytology Disease association Double blind procedure Drug efficacy Drug safety Ethnicity Female Human Human papillomavirus type 11 Human papillomavirus type 16 Human papillomavirus type 18 Human papillomavirus type 6 Human tissue Major clinical study Multicenter study Nonhuman Papillomavirus infection Phase 3 clinical trial Polymerase chain reaction Priority journal Randomized controlled trial Uterine cervix biopsy Uterine cervix carcinoma in situ Adenocarcinoma Cervical intraepithelial neoplasia Double-blind method Follow-up studies Humans Papillomaviridae Papillomavirus infections Papillomavirus vaccines Prognosis Uterine cervical neoplasms Vaginal smears Young adult Adenocarcinoma in situ (ais) Human papillomavirus (hpv) Natural history Vaccine viral Dna
Acceso en línea:	https://repository.urosario.edu.co/handle/10336/24337 https://doi.org/10.1002/ijc.25723

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