A plausibly causal functional lupus-associated risk variant in the STAT1-STAT4 locus

"Systemic lupus erythematosus (SLE or lupus) (OMIM: 152700) is a chronic autoimmune disease with debilitating inflammation that affects multiple organ systems. The STAT1-STAT4 locus is one of the first and most highly replicated genetic loci associated with lupus risk. We performed a fine-mappi...

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Autores Principales: Patel, Zubin H, Lu, Xiaoming, Miller, Daniel, Forney, Carmy R, Lee, Joshua, Lynch, Arthur, Schroeder, Connor, Parks, Lois, Magnusen, Albert F, Chen, Xiaoting, Pujato, Mario, Maddox, Avery, Zoller, Erin E, Namjou, Bahram, Brunner, Hermine I, Henrickson, Michael, Huggins, Jennifer L, Williams, Adrienne H, Ziegler, Julie T, Comeau, Mary E, Marion, Miranda C, Glenn, Stuart B, Adler, Adam, Shen, Nan, Nath, Swapan K, Stevens, Anne M, Freedman, Barry I, Pons-Estel, Bernardo A, Tsao, Betty P, Jacob, Chaim O, Kamen, Diane L, Brown, Elizabeth E, Gilkeson, Gary S, Alarcón, Graciela S, Martin, Javier, Reveille, John D, Anaya, Juan-Manuel, James, Judith A, Sivils, Kathy L, Criswell, Lindsey A, Vilá, Luis M, Petri, Michelle, Scofield, R Hal, Kimberly, Robert P, Edberg, Jeffrey C, Ramsey-Goldman, Rosalind, Bang, So-Young, Lee, Hye-Soon, Bae, Sang-Cheol, Boackle, Susan A, Graham, Deborah Cunninghame, Vyse, Timothy J, Merrill, Joan T, Niewold, Timothy B, Ainsworth, Hannah C, Silverman, Earl D, Weisman, Michael H, Wallace, Daniel J, Raj, Prithvi, Guthridge, Joel M, Gaffney, Patrick M, Kelly, Jennifer A, Alarcón-Riquelme, Marta E, Langefeld, Carl D, Wakeland, Edward K, Kaufman, Kenneth M, Weirauch, Matthew T, Harley, John B, Kottyan, Leah C
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: Oxford University Press 2018
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Acceso en línea:https://repository.urosario.edu.co/handle/10336/24225
https://doi.org/10.1093/hmg/ddy140