"Combined protein-and nucleic acid-level effects of rs1143679 (R77H), a lupus-predisposing variant within ITGAM"

"Integrin alpha M(ITGAM; CD11b) is a component of the macrophage-1 antigen complex, which mediates leukocyte adhesion, migration and phagocytosis as part of the immune system.We previously identified amissense polymorphism, rs1143679 (R77H), strongly associated with systemic lupus erythematosus...

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Detalles Bibliográficos
Autores Principales: "Maiti, Amit K., Kim-Howard, Xana, Motghare, Prasenjeet, Pradhan, Vandana, Chua, Kek Heng, Sun, Celi, Arango-Guerrero, María Teresa, Ghosh, Kanjaksha, Niewold, Timothy B., Harley, John B., Anaya, Juan-Manual, Looger, Loren L., Nath, Swapan K."
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: Oxford University Press 2014
Materias:
Rna
Acceso en línea:https://repository.urosario.edu.co/handle/10336/24222
https://doi.org/10.1093/hmg/ddu106