Evaluation of imputation-based association in and around the integrin-?-M (ITGAM) gene and replication of robust association between a non-synonymous functional variant within ITGAM and systemic lupus erythematosus (SLE)

"We recently identified a novel non-synonymous variant, rs1143679, at exon 3 of the ITGAM gene associated with systemic lupus erythematosus (SLE) susceptibility in European-Americans (EAs) and African-Americans. Using genome-wide association approach, three other studies also independently repo...

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Detalles Bibliográficos
Autores Principales: "Han, Shizhong, Kim-Howard, Xana, Deshmukh, Harshal, Kamatani, Yoichiro, Viswanathan, Parvathi, Guthridge, Joel M., Thomas, Kenaz, Kaufman, Kenneth M., Ojwang, Joshua, Rojas-Villarraga, Adriana, Baca, Vicente, Orozco, Lorena, Rhodes, Benjamin, Choi, Chan-Bum, Gregersen, Peter K., Merrill, Joan T., James, Judith A., Gaffney, Patrick M., Moser, Kathy L., Jacob, Chaim O., Kimberly, Robert P., Harley, John B., Bae, Sang-Choel, Anaya, Juan-Manuel, Alarcón-Riquelme, Marta E., Matsuda, Koichi, Vyse, Timothy J., Nath, Swapan K."
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: 2009
Materias:
Acceso en línea:https://repository.urosario.edu.co/handle/10336/24221
https://doi.org/10.1093/hmg/ddp007