Genetic Influence of PTPN22 R620W Polymorphism in Tuberculosis
The PTPN22 gene codes for an intracellular lymphoid-specific phosphatase (Lyp) that has a negative regulatory effect on T-cell activation. Because Lyp is an important molecule involved in the inflammatory response, and its levels are increased in cells that participate in the immune response against...
Autores Principales: | , , |
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Formato: | Artículo (Article) |
Lenguaje: | Inglés (English) |
Publicado: |
2005
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Materias: | |
Acceso en línea: | https://repository.urosario.edu.co/handle/10336/24216 https://doi.org/10.1016/j.humimm.2005.11.008 |