Is neuralgia a transcriptional channelopathy?

"Neuralgia, is a symptom of some neurological disorders and can be found at any age. It is characterized by paroxysmal and lancinating pain that follows the path of the affected nerve. It can be spontaneous or may be triggered by any type of stimuli. This pain is usually brief but may be severe...

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Autores Principales: Gutiérrez-álvarez É.M., Moreno C.B.
Formato: Capítulo de libro (Book Chapter)
Lenguaje:Inglés (English)
Publicado: "Nova Science Publishers, Inc." 2010
Materias:
Acceso en línea:https://repository.urosario.edu.co/handle/10336/24214
id ir-10336-24214
recordtype dspace
spelling ir-10336-242142020-06-03T22:15:17Z Is neuralgia a transcriptional channelopathy? Gutiérrez-álvarez É.M. Moreno C.B. neuralgia transcriptional channelopathy "Neuralgia, is a symptom of some neurological disorders and can be found at any age. It is characterized by paroxysmal and lancinating pain that follows the path of the affected nerve. It can be spontaneous or may be triggered by any type of stimuli. This pain is usually brief but may be severe, pain-free intervals being common. This symptom is the main characteristic of some neurological entities and, due to its presence and importance, these diseases are thereby known as trigeminal neuralgia, glossopharyngeal neuralgia or postherpetic neuralgia. Neuralgia is caused by irritation or nerve damage arising from inflammation, trauma, surgery, compression by adjacent structures such as tumors, infection and chemical or physical irritation of a nerve, even though the cause remains unknown in most cases. This chapter presents the evidence sustaining the hypothesis that neuralgia is a clinical expression of a transcriptional channelopathy. This will help (in the near future) in designing new drugs orientated towards such target and lead to advances in diagnosing and treating patients who are affected by this important symptom. © 2010 by Nova Science Publishers, Inc." 2010 2020-05-26T00:10:09Z info:eu-repo/semantics/bookPart info:eu-repo/semantics/publishedVersion https://repository.urosario.edu.co/handle/10336/24214 eng info:eu-repo/semantics/openAccess application/pdf "Nova Science Publishers, Inc." instname:Universidad del Rosario reponame:Repositorio Institucional EdocUR
institution EdocUR - Universidad del Rosario
collection DSpace
language Inglés (English)
topic neuralgia
transcriptional
channelopathy
spellingShingle neuralgia
transcriptional
channelopathy
Gutiérrez-álvarez É.M.
Moreno C.B.
Is neuralgia a transcriptional channelopathy?
description "Neuralgia, is a symptom of some neurological disorders and can be found at any age. It is characterized by paroxysmal and lancinating pain that follows the path of the affected nerve. It can be spontaneous or may be triggered by any type of stimuli. This pain is usually brief but may be severe, pain-free intervals being common. This symptom is the main characteristic of some neurological entities and, due to its presence and importance, these diseases are thereby known as trigeminal neuralgia, glossopharyngeal neuralgia or postherpetic neuralgia. Neuralgia is caused by irritation or nerve damage arising from inflammation, trauma, surgery, compression by adjacent structures such as tumors, infection and chemical or physical irritation of a nerve, even though the cause remains unknown in most cases. This chapter presents the evidence sustaining the hypothesis that neuralgia is a clinical expression of a transcriptional channelopathy. This will help (in the near future) in designing new drugs orientated towards such target and lead to advances in diagnosing and treating patients who are affected by this important symptom. © 2010 by Nova Science Publishers, Inc."
format Capítulo de libro (Book Chapter)
author Gutiérrez-álvarez É.M.
Moreno C.B.
author_facet Gutiérrez-álvarez É.M.
Moreno C.B.
author_sort Gutiérrez-álvarez É.M.
title Is neuralgia a transcriptional channelopathy?
title_short Is neuralgia a transcriptional channelopathy?
title_full Is neuralgia a transcriptional channelopathy?
title_fullStr Is neuralgia a transcriptional channelopathy?
title_full_unstemmed Is neuralgia a transcriptional channelopathy?
title_sort is neuralgia a transcriptional channelopathy?
publisher "Nova Science Publishers, Inc."
publishDate 2010
url https://repository.urosario.edu.co/handle/10336/24214
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score 11,392624