ATG7 and ATG9A loss-of-function variants trigger autophagy impairment and ovarian failure

"Purpose: Primary ovarian insufficiency (POI) is a frequent disorder that affects ~1% of women under 40 years of age. POI, which is characterized by the premature depletion of ovarian follicles and elevated plasma levels of follicle-stimulating hormone (FSH), leads to infertility. Although vari...

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Detalles Bibliográficos
Autores Principales: Delcour C., Amazit L., Patino L.C., Magnin F., Fagart J., Delemer B., Young J., Laissue P., Binart N., Beau I.
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: Nature Publishing Group 2019
Acceso en línea: