The H3K9 methylation writer SETDB1 and its reader MPP8 cooperate to silence satellite DNA repeats in mouse embryonic stem cells

"SETDB1 (SET Domain Bifurcated histone lysine methyltransferase 1) is a key lysine methyltransferase (KMT) required in embryonic stem cells (ESCs), where it silences transposable elements and DNA repeats via histone H3 lysine 9 tri-methylation (H3K9me3), independently of DNA methylation. The H3...

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Detalles Bibliográficos
Autores Principales: Cruz-Tapias, Paola, Robin, Philippe, Pontis, Julien, Del Maestro, Laurence, Ait-Si-Ali, Slimane
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: MDPI AG 2019
Materias:
Acceso en línea:https://repository.urosario.edu.co/handle/10336/24143
https://doi.org/10.3390/genes10100750