Imagen de Portada

PTPN22 C1858T polymorphism in Colombian patients with autoimmune diseases

A functional single nucleotide polymorphism (SNP) C1858T in the protein tyrosine phosphatase nonreceptor 22 (PTPN22) gene encoding an intracellular phosphatase with negative regulatory effects on T-cell activation is associated with some autoimmune diseases in Caucasians. Taking into account firstly...

Descripción completa

Detalles Bibliográficos
Autores Principales: Gomez L.M., Anaya, Juan-Manuel, Gonzalez C.I., Pineda-Tamayo R., Otero W., Arango A., Martín J.
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: 2005
Materias:
Protein tyrosine phosphatase
Protein tyrosine phosphatase nonreceptor 22
Unclassified drug
Article
Autoimmune disease
Autoimmunity
Caucasian
Colombia
Controlled study
Dna polymorphism
Gene frequency
Gene replication
Genetic code
Genotype
Human
Immunogenetics
Insulin dependent diabetes mellitus
Intracellular space
Major clinical study
Phenotype
Priority journal
Real time polymerase chain reaction
Rheumatoid arthritis
Risk factor
Single nucleotide polymorphism
Sjoegren syndrome
Systemic lupus erythematosus
T lymphocyte activation
Adult
Aged
Alleles
Autoimmune diseases
European continental ancestry group
Female
Humans
Male
Middle aged
Protein-tyrosine-phosphatase
Sjogren's syndrome
Diabetes mellitus
Ptpn22
Sjögren's syndrome
single nucleotide
rheumatoid
type 1
systemic
Arthritis
Lupus erythematosus
Polymorphism
Acceso en línea:https://repository.urosario.edu.co/handle/10336/24138
https://doi.org/10.1038/sj.gene.6364261

Internet

https://repository.urosario.edu.co/handle/10336/24138
https://doi.org/10.1038/sj.gene.6364261

Ejemplares similares