Genetic association of CD247 (CD3?) with SLE in a large-scale multiethnic study

"A classic T-cell phenotype in systemic lupus erythematosus (SLE) is the downregulation and replacement of the CD3? chain that alters T-cell receptor signaling. However, genetic associations with SLE in the human CD247 locus that encodes CD3? are not well established and require replication in...

Descripción completa

Detalles Bibliográficos
Autores Principales: Martins, M, Williams, A H, Comeau, M, Marion, M, Ziegler, J T, Freedman, B I, Merrill, J T, Glenn, S B, Kelly, J A, Sivils, K M, James, J A, Guthridge, J M, Alarcón-Riquelme, M E, Bae, S-C, Kim, J-H, Kim, D, Anaya, Juan-Manuel, Boackle, S A, Criswell, L A, Kimberly, R P, Alarcón, G S, Brown, E E, Vilá, L M, Petri, M A, Ramsey-Goldman, R, Niewold, T B, Tsao, B P, Gilkeson, G S, Kamen, D L, Jacob, C O, Stevens, A M, Gaffney, P M, Harley, J B, Langefeld, C D, Fesel, C
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: Nature Publishing Group 2015
Materias:
CD3
Acceso en línea:https://repository.urosario.edu.co/handle/10336/24137
https://doi.org/10.1038/gene.2014.73