Gender differences in latin-american patients with rheumatoid arthritis
Background: Data on the effect of gender in rheumatoid arthritis (RA) in non-Caucasian populations is scarce. Latin America and the Caribbean (LAC) is a large population with unique characteristics, including high admixture. Objective: Our aim was to examine the effect of gender in patients with RA...
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Acceso en línea: | https://repository.urosario.edu.co/handle/10336/24124 https://doi.org/10.1016/j.genm.2012.10.005 |
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ir-10336-241242022-05-02T12:37:13Z Gender differences in latin-american patients with rheumatoid arthritis Barragán-Martínez, Carolina Amaya-Amaya, Jenny Pineda-Tamayo, Ricardo Mantilla, Rubén D. la Hoz, Juan Castellanos-de Bernal-Macías, Santiago Rojas-Villarraga, Adriana Anaya, Juan-Manuel Abatacept Adalimumab Azathioprine Chloroquine Cyclosporin Etanercept Gold salt Hydroxychloroquine Leflunomide Methotrexate Penicillamine Rituximab Salazosulfapyridine Steroid Tocilizumab Abdominal obesity Alternative medicine Article Bivariate analysis Central america Clinical assessment Colombia Cross-sectional study Data analysis Data extraction Disease association Household Human Latin american medicine Medline Outcome assessment Prevalence Priority journal Publication Quality control Rheumatoid arthritis Sex difference South and central america Systematic review Gender Latin america Polyautoimmunity Rheumatoid arthritis Systematic review Background: Data on the effect of gender in rheumatoid arthritis (RA) in non-Caucasian populations is scarce. Latin America and the Caribbean (LAC) is a large population with unique characteristics, including high admixture. Objective: Our aim was to examine the effect of gender in patients with RA in LAC. Methods: This was a 2-phase study. First we conducted a cross-sectional and analytical study in which 1128 consecutive Colombian patients with RA were assessed. Second, a systematic review of the literature was done to evaluate the effect of gender in LAC patients with RA. Results: Our results show a high prevalence of RA in LAC women with a ratio of 5.2 women per man. Colombian women with RA are more at risk of having an early age at onset and developing polyautoimmunity and abdominal obesity, and they perform more household duties than their male counterparts. However, male gender was associated with the presence of extra-articular manifestations. Of a total of 641 potentially relevant articles, 38 were considered for final analysis, in which several factors and outcomes related to gender were identified. Conclusions: RA in LAC women is not only more common but presents with some clinical characteristics that differ from RA presentation in men. Some of those characteristics could explain the high rates of disability and worse prognosis observed in women with RA in LAC. © 2012 Elsevier HS Journals, Inc. 2012 2020-05-26T00:08:53Z info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion https://repository.urosario.edu.co/handle/10336/24124 https://doi.org/10.1016/j.genm.2012.10.005 eng info:eu-repo/semantics/openAccess application/pdf Excerpta Medica Inc. instname:Universidad del Rosario |
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EdocUR - Universidad del Rosario |
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DSpace |
language |
Inglés (English) |
topic |
Abatacept Adalimumab Azathioprine Chloroquine Cyclosporin Etanercept Gold salt Hydroxychloroquine Leflunomide Methotrexate Penicillamine Rituximab Salazosulfapyridine Steroid Tocilizumab Abdominal obesity Alternative medicine Article Bivariate analysis Central america Clinical assessment Colombia Cross-sectional study Data analysis Data extraction Disease association Household Human Latin american medicine Medline Outcome assessment Prevalence Priority journal Publication Quality control Rheumatoid arthritis Sex difference South and central america Systematic review Gender Latin america Polyautoimmunity Rheumatoid arthritis Systematic review |
spellingShingle |
Abatacept Adalimumab Azathioprine Chloroquine Cyclosporin Etanercept Gold salt Hydroxychloroquine Leflunomide Methotrexate Penicillamine Rituximab Salazosulfapyridine Steroid Tocilizumab Abdominal obesity Alternative medicine Article Bivariate analysis Central america Clinical assessment Colombia Cross-sectional study Data analysis Data extraction Disease association Household Human Latin american medicine Medline Outcome assessment Prevalence Priority journal Publication Quality control Rheumatoid arthritis Sex difference South and central america Systematic review Gender Latin america Polyautoimmunity Rheumatoid arthritis Systematic review Barragán-Martínez, Carolina Amaya-Amaya, Jenny Pineda-Tamayo, Ricardo Mantilla, Rubén D. la Hoz, Juan Castellanos-de Bernal-Macías, Santiago Rojas-Villarraga, Adriana Anaya, Juan-Manuel Gender differences in latin-american patients with rheumatoid arthritis |
description |
Background: Data on the effect of gender in rheumatoid arthritis (RA) in non-Caucasian populations is scarce. Latin America and the Caribbean (LAC) is a large population with unique characteristics, including high admixture. Objective: Our aim was to examine the effect of gender in patients with RA in LAC. Methods: This was a 2-phase study. First we conducted a cross-sectional and analytical study in which 1128 consecutive Colombian patients with RA were assessed. Second, a systematic review of the literature was done to evaluate the effect of gender in LAC patients with RA. Results: Our results show a high prevalence of RA in LAC women with a ratio of 5.2 women per man. Colombian women with RA are more at risk of having an early age at onset and developing polyautoimmunity and abdominal obesity, and they perform more household duties than their male counterparts. However, male gender was associated with the presence of extra-articular manifestations. Of a total of 641 potentially relevant articles, 38 were considered for final analysis, in which several factors and outcomes related to gender were identified. Conclusions: RA in LAC women is not only more common but presents with some clinical characteristics that differ from RA presentation in men. Some of those characteristics could explain the high rates of disability and worse prognosis observed in women with RA in LAC. © 2012 Elsevier HS Journals, Inc. |
format |
Artículo (Article) |
author |
Barragán-Martínez, Carolina Amaya-Amaya, Jenny Pineda-Tamayo, Ricardo Mantilla, Rubén D. la Hoz, Juan Castellanos-de Bernal-Macías, Santiago Rojas-Villarraga, Adriana Anaya, Juan-Manuel |
author_facet |
Barragán-Martínez, Carolina Amaya-Amaya, Jenny Pineda-Tamayo, Ricardo Mantilla, Rubén D. la Hoz, Juan Castellanos-de Bernal-Macías, Santiago Rojas-Villarraga, Adriana Anaya, Juan-Manuel |
author_sort |
Barragán-Martínez, Carolina |
title |
Gender differences in latin-american patients with rheumatoid arthritis |
title_short |
Gender differences in latin-american patients with rheumatoid arthritis |
title_full |
Gender differences in latin-american patients with rheumatoid arthritis |
title_fullStr |
Gender differences in latin-american patients with rheumatoid arthritis |
title_full_unstemmed |
Gender differences in latin-american patients with rheumatoid arthritis |
title_sort |
gender differences in latin-american patients with rheumatoid arthritis |
publisher |
Excerpta Medica Inc. |
publishDate |
2012 |
url |
https://repository.urosario.edu.co/handle/10336/24124 https://doi.org/10.1016/j.genm.2012.10.005 |
_version_ |
1740172508739403776 |
score |
12,131701 |