Mayaro: an emerging viral threat?

Mayaro virus (MAYV), an enveloped RNA virus, belongs to the Togaviridae family and Alphavirus genus. This arthropod-borne virus (Arbovirus) is similar to Chikungunya (CHIKV), Dengue (DENV), and Zika virus (ZIKV). The term “ChikDenMaZika syndrome” has been coined for clinically suspected arboviruses,...

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Autores Principales: Acosta-Ampudia, Yeny, Monsalve, Diana M., Pacheco Nieva, Yovana, Rodríguez, Yhojan, Anaya, Juan-Manuel, Ramirez-Santana, Carolina
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://repository.urosario.edu.co/handle/10336/23916
https://doi.org/10.1038/s41426-018-0163-5
id ir-10336-23916
recordtype dspace
spelling ir-10336-239162022-05-02T12:37:16Z Mayaro: an emerging viral threat? Acosta-Ampudia, Yeny Monsalve, Diana M. Pacheco Nieva, Yovana Rodríguez, Yhojan Anaya, Juan-Manuel Ramirez-Santana, Carolina Alphavirus Arbovirus Arthralgia Bleeding Chikungunya virus Cross reaction Dengue virus Fever Genomics Human Life threat Maculopapular rash Mayaro virus Mixed infection Myocarditis Neurological complication Nonhuman Polyarthritis Priority journal Review South America Togaviridae Virus load Virus morphology Zika virus Alphavirus infection Animal Classification Communicable disease Genetics Isolation and purification Physiology Virology Alphavirus Alphavirus Infections Animals Humans South America Emerging Communicable Diseases Mayaro virus (MAYV), an enveloped RNA virus, belongs to the Togaviridae family and Alphavirus genus. This arthropod-borne virus (Arbovirus) is similar to Chikungunya (CHIKV), Dengue (DENV), and Zika virus (ZIKV). The term “ChikDenMaZika syndrome” has been coined for clinically suspected arboviruses, which have arisen as a consequence of the high viral burden, viral co-infection, and co-circulation in South America. In most cases, MAYV disease is nonspecific, mild, and self-limited. Fever, arthralgia, and maculopapular rash are among the most common symptoms described, being largely indistinguishable from those caused by other arboviruses. However, severe manifestations of the infection have been reported, such as chronic polyarthritis, neurological complications, hemorrhage, myocarditis, and even death. Currently, there are no specific commercial tools for the diagnosis of MAYV, and the use of serological methods can be affected by cross-reactivity and the window period. A diagnosis based on clinical and epidemiological data alone is still premature. Therefore, new entomological research is warranted, and new highly specific molecular diagnostic methods should be developed. This comprehensive review is intended to encourage public health authorities and scientific communities to actively work on diagnosing, preventing, and treating MAYV infection. © 2018, The Author(s). 2018 2020-05-26T00:06:39Z info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion 22221751 https://repository.urosario.edu.co/handle/10336/23916 https://doi.org/10.1038/s41426-018-0163-5 eng info:eu-repo/semantics/openAccess application/pdf Nature Publishing Group instname:Universidad del Rosario
institution EdocUR - Universidad del Rosario
collection DSpace
language Inglés (English)
topic Alphavirus
Arbovirus
Arthralgia
Bleeding
Chikungunya virus
Cross reaction
Dengue virus
Fever
Genomics
Human
Life threat
Maculopapular rash
Mayaro virus
Mixed infection
Myocarditis
Neurological complication
Nonhuman
Polyarthritis
Priority journal
Review
South America
Togaviridae
Virus load
Virus morphology
Zika virus
Alphavirus infection
Animal
Classification
Communicable disease
Genetics
Isolation and purification
Physiology
Virology
Alphavirus
Alphavirus Infections
Animals
Humans
South America
Emerging
Communicable Diseases
spellingShingle Alphavirus
Arbovirus
Arthralgia
Bleeding
Chikungunya virus
Cross reaction
Dengue virus
Fever
Genomics
Human
Life threat
Maculopapular rash
Mayaro virus
Mixed infection
Myocarditis
Neurological complication
Nonhuman
Polyarthritis
Priority journal
Review
South America
Togaviridae
Virus load
Virus morphology
Zika virus
Alphavirus infection
Animal
Classification
Communicable disease
Genetics
Isolation and purification
Physiology
Virology
Alphavirus
Alphavirus Infections
Animals
Humans
South America
Emerging
Communicable Diseases
Acosta-Ampudia, Yeny
Monsalve, Diana M.
Pacheco Nieva, Yovana
Rodríguez, Yhojan
Anaya, Juan-Manuel
Ramirez-Santana, Carolina
Mayaro: an emerging viral threat?
description Mayaro virus (MAYV), an enveloped RNA virus, belongs to the Togaviridae family and Alphavirus genus. This arthropod-borne virus (Arbovirus) is similar to Chikungunya (CHIKV), Dengue (DENV), and Zika virus (ZIKV). The term “ChikDenMaZika syndrome” has been coined for clinically suspected arboviruses, which have arisen as a consequence of the high viral burden, viral co-infection, and co-circulation in South America. In most cases, MAYV disease is nonspecific, mild, and self-limited. Fever, arthralgia, and maculopapular rash are among the most common symptoms described, being largely indistinguishable from those caused by other arboviruses. However, severe manifestations of the infection have been reported, such as chronic polyarthritis, neurological complications, hemorrhage, myocarditis, and even death. Currently, there are no specific commercial tools for the diagnosis of MAYV, and the use of serological methods can be affected by cross-reactivity and the window period. A diagnosis based on clinical and epidemiological data alone is still premature. Therefore, new entomological research is warranted, and new highly specific molecular diagnostic methods should be developed. This comprehensive review is intended to encourage public health authorities and scientific communities to actively work on diagnosing, preventing, and treating MAYV infection. © 2018, The Author(s).
format Artículo (Article)
author Acosta-Ampudia, Yeny
Monsalve, Diana M.
Pacheco Nieva, Yovana
Rodríguez, Yhojan
Anaya, Juan-Manuel
Ramirez-Santana, Carolina
author_facet Acosta-Ampudia, Yeny
Monsalve, Diana M.
Pacheco Nieva, Yovana
Rodríguez, Yhojan
Anaya, Juan-Manuel
Ramirez-Santana, Carolina
author_sort Acosta-Ampudia, Yeny
title Mayaro: an emerging viral threat?
title_short Mayaro: an emerging viral threat?
title_full Mayaro: an emerging viral threat?
title_fullStr Mayaro: an emerging viral threat?
title_full_unstemmed Mayaro: an emerging viral threat?
title_sort mayaro: an emerging viral threat?
publisher Nature Publishing Group
publishDate 2018
url https://repository.urosario.edu.co/handle/10336/23916
https://doi.org/10.1038/s41426-018-0163-5
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