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The simultaneous presence of IL-1B and TNFA two-positions risk haplotypes enhances the susceptibility for celiac disease

To assess the joint contribution of interleukin 1 beta (IL-1B) and tumor necrosis factor alpha (TNF?) to the genetic risk of developing celiac disease (CD), we analyzed four biallelic polymorphisms of TNFA and IL-1B genes in 228 patients and 244 healthy controls. The individual contribution of TNFA...

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Detalles Bibliográficos
Autores Principales: Cherñavsky, Alejandra Claudia, Páez, María Carolina, Periolo, Natalia, Correa, Paula, Guillén, Laura, Niveloni, Sonia Isabel, Mauriño, Eduardo, Bai, Julio César, Anaya, Juan-Manuel
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: 2008
Materias:
HLA DQA1 antigen
HLA DQB1 antigen
Interleukin 1beta
Tumor necrosis factor alpha
Adult
Aged
Article
Celiac disease
Controlled study
Disease course
Disease predisposition
Female
Gene frequency
Gene linkage disequilibrium
Gene location
Genetic risk
Haplotype
Heterozygote
Human
Major clinical study
Male
Priority journal
Single nucleotide polymorphism
Adolescent
Alleles
Celiac Disease
Gene Frequency
Genetic Predisposition to Disease
Genotype
Haplotypes
HLA-DQ Antigens
Humans
Interleukin-1beta
Middle Aged
Tumor Necrosis Factor-alpha
IL-1B
Polymorphisms
TNFA
DNA
Genetic
Polymorphism
Sequence Analysis
Acceso en línea:https://repository.urosario.edu.co/handle/10336/23831
https://doi.org/10.1016/j.cyto.2008.01.015

Internet

https://repository.urosario.edu.co/handle/10336/23831
https://doi.org/10.1016/j.cyto.2008.01.015

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