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Genetic associations of leptin-related polymorphisms with systemic lupus erythematosus

Leptin is abnormally elevated in the plasma of patients with systemic lupus erythematosus (SLE), where it is thought to promote and/or sustain pro-inflammatory responses. Whether this association could reflect an increased genetic susceptibility to develop SLE is not known, and studies of genetic as...

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Detalles Bibliográficos
Autores Principales: Zhao, Jian, Wu, Hui, Langefeld, Carl D., Kaufman, Kenneth M., Kelly, Jennifer A., Bae, Sang-Cheol, networks, Marta E. Alarcón-Riquelme for the BIOLUPUS and GENLES, Alarcón, Graciela S., Anaya, Juan-Manuel, Criswell, Lindsey A., Freedman, Barry I., Kamen, Diane L., Gilkeson, Gary S., Jacob, Chaim O., James, Judith A., Merrill, Joan T., Gaffney, Patrick M., Sivils, Kathy Moser, Niewold, Timothy B., Petri, Michelle, Song, Seung Taek, Jeong, Hye-jin, Ramsey-Goldman, Rosalind, Reveille, John D., Scofield, R. Hal, Stevens, Anne M., Boackle, Susan A., Vilá, Luis M., Chang, Deh-Ming, Song, Yeong Wook, Vyse, Timothy J., Harley, John B., Brown, Elizabeth E., Edberg, Jeffrey C., Kimberly, Robert P., Hahn, Bevra H., Grossman, Jennifer M., Tsao, Betty P., La Cava, Antonio
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: Academic Press Inc. 2015
Materias:
Leptin
African american
Article
Controlled study
Dna determination
East asian
European american
Gene
Genetic association
Genetic risk
Genetic susceptibility
Genotype
Ghsr gene
Hispanic
Human
Inflammation
Lep gene
Lepr gene
Major clinical study
Pparg gene
Priority journal
Single nucleotide polymorphism
Systemic lupus erythematosus
Case control study
Genetic predisposition
Genetics
Case-control studies
Genetic predisposition to disease
Humans
Gene polymorphisms
Leptin pathway
systemic
single nucleotide
Lupus erythematosus
Polymorphism
Acceso en línea:https://repository.urosario.edu.co/handle/10336/23683
https://doi.org/10.1016/j.clim.2015.09.007

Internet

https://repository.urosario.edu.co/handle/10336/23683
https://doi.org/10.1016/j.clim.2015.09.007

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