Genetic associations of leptin-related polymorphisms with systemic lupus erythematosus

Leptin is abnormally elevated in the plasma of patients with systemic lupus erythematosus (SLE), where it is thought to promote and/or sustain pro-inflammatory responses. Whether this association could reflect an increased genetic susceptibility to develop SLE is not known, and studies of genetic as...

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Autores Principales: Zhao, Jian, Wu, Hui, Langefeld, Carl D., Kaufman, Kenneth M., Kelly, Jennifer A., Bae, Sang-Cheol, networks, Marta E. Alarcón-Riquelme for the BIOLUPUS and GENLES, Alarcón, Graciela S., Anaya, Juan-Manuel, Criswell, Lindsey A., Freedman, Barry I., Kamen, Diane L., Gilkeson, Gary S., Jacob, Chaim O., James, Judith A., Merrill, Joan T., Gaffney, Patrick M., Sivils, Kathy Moser, Niewold, Timothy B., Petri, Michelle, Song, Seung Taek, Jeong, Hye-jin, Ramsey-Goldman, Rosalind, Reveille, John D., Scofield, R. Hal, Stevens, Anne M., Boackle, Susan A., Vilá, Luis M., Chang, Deh-Ming, Song, Yeong Wook, Vyse, Timothy J., Harley, John B., Brown, Elizabeth E., Edberg, Jeffrey C., Kimberly, Robert P., Hahn, Bevra H., Grossman, Jennifer M., Tsao, Betty P., La Cava, Antonio
Formato: Artículo (Article)
Lenguaje:Inglés (English)
Publicado: Academic Press Inc. 2015
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