Autonomic symptoms following Zika virus infection
Purpose: To determine if autonomic symptoms are associated with previous Zika virus infection. Methods: Case–control study including 35 patients with Zika virus infection without evidence of neurological disease and 105 controls. Symptoms of autonomic dysfunction were assessed with the composite aut...
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Dr. Dietrich Steinkopff Verlag GmbH and Co. KG
2018
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Acceso en línea: | https://repository.urosario.edu.co/handle/10336/23676 https://doi.org/10.1007/s10286-018-0515-1 |
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ir-10336-236762022-05-02T12:37:16Z Autonomic symptoms following Zika virus infection Rodríguez Y. Rojas M. Ramirez-Santana, Carolina Acosta-Ampudia, Yeny Monsalve, Diana M. Anaya, Juan-Manuel Immunoglobulin G antibody Immunoglobulin M antibody Neutralizing antibody Adult Article Autonomic dysfunction Bladder disease Case control study Clinical article Composite autonomic symptom score 31 Controlled study Disease association Female Human Male Orthostatic intolerance Patient-reported outcome Secretomotor disease Zika fever Autonomic neuropathy Complication Middle aged Pathophysiology Retrospective study Zika fever Adult Autonomic Nervous System Diseases Case-Control Studies Female Humans Male Middle Aged Retrospective Studies Zika Virus Infection Autonomic symptoms COMPASS 31 Dysautonomia Flavivirus Zika virus Purpose: To determine if autonomic symptoms are associated with previous Zika virus infection. Methods: Case–control study including 35 patients with Zika virus infection without evidence of neurological disease and 105 controls. Symptoms of autonomic dysfunction were assessed with the composite autonomic symptom scale 31 (COMPASS-31). Results: Patients with previous Zika virus infection had significantly higher COMPASS-31 score than controls regardless of age and sex (p = 0.007). The main drivers for the higher scores where orthostatic intolerance (p = 0.003), secretomotor (p = 0.04) and bladder symptoms (p less than 0.001). Conclusion: Zika virus infection is associated with autonomic dysfunction. The mechanisms remain to be elucidated. © 2018, Springer-Verlag GmbH Germany, part of Springer Nature. 2018 2020-05-26T00:04:19Z info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion 09599851 16191560 https://repository.urosario.edu.co/handle/10336/23676 https://doi.org/10.1007/s10286-018-0515-1 eng info:eu-repo/semantics/openAccess application/pdf Dr. Dietrich Steinkopff Verlag GmbH and Co. KG instname:Universidad del Rosario |
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EdocUR - Universidad del Rosario |
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language |
Inglés (English) |
topic |
Immunoglobulin G antibody Immunoglobulin M antibody Neutralizing antibody Adult Article Autonomic dysfunction Bladder disease Case control study Clinical article Composite autonomic symptom score 31 Controlled study Disease association Female Human Male Orthostatic intolerance Patient-reported outcome Secretomotor disease Zika fever Autonomic neuropathy Complication Middle aged Pathophysiology Retrospective study Zika fever Adult Autonomic Nervous System Diseases Case-Control Studies Female Humans Male Middle Aged Retrospective Studies Zika Virus Infection Autonomic symptoms COMPASS 31 Dysautonomia Flavivirus Zika virus |
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Immunoglobulin G antibody Immunoglobulin M antibody Neutralizing antibody Adult Article Autonomic dysfunction Bladder disease Case control study Clinical article Composite autonomic symptom score 31 Controlled study Disease association Female Human Male Orthostatic intolerance Patient-reported outcome Secretomotor disease Zika fever Autonomic neuropathy Complication Middle aged Pathophysiology Retrospective study Zika fever Adult Autonomic Nervous System Diseases Case-Control Studies Female Humans Male Middle Aged Retrospective Studies Zika Virus Infection Autonomic symptoms COMPASS 31 Dysautonomia Flavivirus Zika virus Rodríguez Y. Rojas M. Ramirez-Santana, Carolina Acosta-Ampudia, Yeny Monsalve, Diana M. Anaya, Juan-Manuel Autonomic symptoms following Zika virus infection |
description |
Purpose: To determine if autonomic symptoms are associated with previous Zika virus infection. Methods: Case–control study including 35 patients with Zika virus infection without evidence of neurological disease and 105 controls. Symptoms of autonomic dysfunction were assessed with the composite autonomic symptom scale 31 (COMPASS-31). Results: Patients with previous Zika virus infection had significantly higher COMPASS-31 score than controls regardless of age and sex (p = 0.007). The main drivers for the higher scores where orthostatic intolerance (p = 0.003), secretomotor (p = 0.04) and bladder symptoms (p less than 0.001). Conclusion: Zika virus infection is associated with autonomic dysfunction. The mechanisms remain to be elucidated. © 2018, Springer-Verlag GmbH Germany, part of Springer Nature. |
format |
Artículo (Article) |
author |
Rodríguez Y. Rojas M. Ramirez-Santana, Carolina Acosta-Ampudia, Yeny Monsalve, Diana M. Anaya, Juan-Manuel |
author_facet |
Rodríguez Y. Rojas M. Ramirez-Santana, Carolina Acosta-Ampudia, Yeny Monsalve, Diana M. Anaya, Juan-Manuel |
author_sort |
Rodríguez Y. |
title |
Autonomic symptoms following Zika virus infection |
title_short |
Autonomic symptoms following Zika virus infection |
title_full |
Autonomic symptoms following Zika virus infection |
title_fullStr |
Autonomic symptoms following Zika virus infection |
title_full_unstemmed |
Autonomic symptoms following Zika virus infection |
title_sort |
autonomic symptoms following zika virus infection |
publisher |
Dr. Dietrich Steinkopff Verlag GmbH and Co. KG |
publishDate |
2018 |
url |
https://repository.urosario.edu.co/handle/10336/23676 https://doi.org/10.1007/s10286-018-0515-1 |
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1740172507919417344 |
score |
12,131701 |